1NF8

Crystal structure of PhzD protein active site mutant with substrate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002047	biological_process	phenazine biosynthetic process
A	0008908	molecular_function	isochorismatase activity
A	0016787	molecular_function	hydrolase activity
A	0017000	biological_process	antibiotic biosynthetic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton donor => ECO:0000250|UniProtKB:P0DPC1

Chain	Residue	Details
A	ALA38

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site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P0DPC1

Chain	Residue	Details
A	GLN78
A	ARG87
A	LYS122
A	TYR151

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues	3
Details	M-CSA 859

Chain	Residue	Details
A	HIS37	electrostatic stabiliser, steric role
A	ALA38	electrostatic stabiliser, proton shuttle (general acid/base)
A	LYS122	proton shuttle (general acid/base)

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