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1NEP

Crystal Structure Analysis of the Bovine NPC2 (Niemann-Pick C2) Protein

Functional Information from GO Data
ChainGOidnamespacecontents
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005764cellular_componentlysosome
A0005783cellular_componentendoplasmic reticulum
A0006869biological_processlipid transport
A0008203biological_processcholesterol metabolic process
A0009615biological_processresponse to virus
A0010467biological_processgene expression
A0010878biological_processcholesterol storage
A0015485molecular_functioncholesterol binding
A0015918biological_processsterol transport
A0016125biological_processsterol metabolic process
A0019899molecular_functionenzyme binding
A0030301biological_processcholesterol transport
A0032366biological_processintracellular sterol transport
A0032367biological_processintracellular cholesterol transport
A0032934molecular_functionsterol binding
A0033344biological_processcholesterol efflux
A0042632biological_processcholesterol homeostasis
A0120020molecular_functioncholesterol transfer activity
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q9Z0J0
ChainResidueDetails
ALYS97

site_idSWS_FT_FI2
Number of Residues1
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:12591954, ECO:0000269|PubMed:17573352, ECO:0007744|PDB:1NEP, ECO:0007744|PDB:2HKA
ChainResidueDetails
AASN39

222624

PDB entries from 2024-07-17

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