1NAN

MCH CLASS I H-2KB MOLECULE COMPLEXED WITH PBM1 PEPTIDE

Functional Information from GO Data

Chain	GOid	namespace	contents
I	0001913	biological_process	T cell mediated cytotoxicity
I	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
I	0002237	biological_process	response to molecule of bacterial origin
I	0002376	biological_process	immune system process
I	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
I	0002481	biological_process	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
I	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
I	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
I	0002726	biological_process	positive regulation of T cell cytokine production
I	0005198	molecular_function	structural molecule activity
I	0005515	molecular_function	protein binding
I	0005576	cellular_component	extracellular region
I	0005615	cellular_component	extracellular space
I	0005765	cellular_component	lysosomal membrane
I	0005794	cellular_component	Golgi apparatus
I	0005829	cellular_component	cytosol
I	0005886	cellular_component	plasma membrane
I	0006826	biological_process	iron ion transport
I	0006879	biological_process	intracellular iron ion homeostasis
I	0006955	biological_process	immune response
I	0006968	biological_process	cellular defense response
I	0007608	biological_process	sensory perception of smell
I	0007611	biological_process	learning or memory
I	0009897	cellular_component	external side of plasma membrane
I	0010038	biological_process	response to metal ion
I	0010977	biological_process	negative regulation of neuron projection development
I	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
I	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
I	0023026	molecular_function	MHC class II protein complex binding
I	0030670	cellular_component	phagocytic vesicle membrane
I	0031902	cellular_component	late endosome membrane
I	0033077	biological_process	T cell differentiation in thymus
I	0033572	biological_process	transferrin transport
I	0034756	biological_process	regulation of iron ion transport
I	0034757	biological_process	negative regulation of iron ion transport
I	0042026	biological_process	protein refolding
I	0042605	molecular_function	peptide antigen binding
I	0042612	cellular_component	MHC class I protein complex
I	0042613	cellular_component	MHC class II protein complex
I	0042802	molecular_function	identical protein binding
I	0042803	molecular_function	protein homodimerization activity
I	0042824	cellular_component	MHC class I peptide loading complex
I	0045646	biological_process	regulation of erythrocyte differentiation
I	0048260	biological_process	positive regulation of receptor-mediated endocytosis
I	0048261	biological_process	negative regulation of receptor-mediated endocytosis
I	0050680	biological_process	negative regulation of epithelial cell proliferation
I	0050768	biological_process	negative regulation of neurogenesis
I	0050778	biological_process	positive regulation of immune response
I	0050870	biological_process	positive regulation of T cell activation
I	0051289	biological_process	protein homotetramerization
I	0060586	biological_process	multicellular organismal-level iron ion homeostasis
I	0071281	biological_process	cellular response to iron ion
I	0071283	biological_process	cellular response to iron(III) ion
I	0071316	biological_process	cellular response to nicotine
I	1990000	biological_process	amyloid fibril formation
I	1990712	cellular_component	HFE-transferrin receptor complex
I	2000774	biological_process	positive regulation of cellular senescence
I	2000978	biological_process	negative regulation of forebrain neuron differentiation
P	0001913	biological_process	T cell mediated cytotoxicity
P	0001916	biological_process	positive regulation of T cell mediated cytotoxicity
P	0002237	biological_process	response to molecule of bacterial origin
P	0002376	biological_process	immune system process
P	0002474	biological_process	antigen processing and presentation of peptide antigen via MHC class I
P	0002481	biological_process	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
P	0002502	biological_process	peptide antigen assembly with MHC class I protein complex
P	0002503	biological_process	peptide antigen assembly with MHC class II protein complex
P	0002726	biological_process	positive regulation of T cell cytokine production
P	0005198	molecular_function	structural molecule activity
P	0005515	molecular_function	protein binding
P	0005576	cellular_component	extracellular region
P	0005615	cellular_component	extracellular space
P	0005765	cellular_component	lysosomal membrane
P	0005794	cellular_component	Golgi apparatus
P	0005829	cellular_component	cytosol
P	0005886	cellular_component	plasma membrane
P	0006826	biological_process	iron ion transport
P	0006879	biological_process	intracellular iron ion homeostasis
P	0006955	biological_process	immune response
P	0006968	biological_process	cellular defense response
P	0007608	biological_process	sensory perception of smell
P	0007611	biological_process	learning or memory
P	0009897	cellular_component	external side of plasma membrane
P	0010038	biological_process	response to metal ion
P	0010977	biological_process	negative regulation of neuron projection development
P	0019885	biological_process	antigen processing and presentation of endogenous peptide antigen via MHC class I
P	0019886	biological_process	antigen processing and presentation of exogenous peptide antigen via MHC class II
P	0023026	molecular_function	MHC class II protein complex binding
P	0030670	cellular_component	phagocytic vesicle membrane
P	0031902	cellular_component	late endosome membrane
P	0033077	biological_process	T cell differentiation in thymus
P	0033572	biological_process	transferrin transport
P	0034756	biological_process	regulation of iron ion transport
P	0034757	biological_process	negative regulation of iron ion transport
P	0042026	biological_process	protein refolding
P	0042605	molecular_function	peptide antigen binding
P	0042612	cellular_component	MHC class I protein complex
P	0042613	cellular_component	MHC class II protein complex
P	0042802	molecular_function	identical protein binding
P	0042803	molecular_function	protein homodimerization activity
P	0042824	cellular_component	MHC class I peptide loading complex
P	0045646	biological_process	regulation of erythrocyte differentiation
P	0048260	biological_process	positive regulation of receptor-mediated endocytosis
P	0048261	biological_process	negative regulation of receptor-mediated endocytosis
P	0050680	biological_process	negative regulation of epithelial cell proliferation
P	0050768	biological_process	negative regulation of neurogenesis
P	0050778	biological_process	positive regulation of immune response
P	0050870	biological_process	positive regulation of T cell activation
P	0051289	biological_process	protein homotetramerization
P	0060586	biological_process	multicellular organismal-level iron ion homeostasis
P	0071281	biological_process	cellular response to iron ion
P	0071283	biological_process	cellular response to iron(III) ion
P	0071316	biological_process	cellular response to nicotine
P	1990000	biological_process	amyloid fibril formation
P	1990712	cellular_component	HFE-transferrin receptor complex
P	2000774	biological_process	positive regulation of cellular senescence
P	2000978	biological_process	negative regulation of forebrain neuron differentiation

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACRVKH

Chain	Residue	Details
P	TYR78-HIS84
H	TYR257-HIS263

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19349973, ECO:0000269|PubMed:7306483

Chain	Residue	Details
H	ASN86
L	ASN86

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site_id	SWS_FT_FI2
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:7306483

Chain	Residue	Details
H	ASN176
L	ASN176

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