1N3T
Biosynthesis of pteridins. Reaction mechanism of GTP cyclohydrolase I
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003934 | molecular_function | GTP cyclohydrolase I activity |
A | 0005525 | molecular_function | GTP binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0005829 | cellular_component | cytosol |
A | 0006729 | biological_process | tetrahydrobiopterin biosynthetic process |
A | 0006730 | biological_process | one-carbon metabolic process |
A | 0008270 | molecular_function | zinc ion binding |
A | 0008616 | biological_process | queuosine biosynthetic process |
A | 0016787 | molecular_function | hydrolase activity |
A | 0032991 | cellular_component | protein-containing complex |
A | 0042802 | molecular_function | identical protein binding |
A | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
A | 0046872 | molecular_function | metal ion binding |
B | 0003934 | molecular_function | GTP cyclohydrolase I activity |
B | 0005525 | molecular_function | GTP binding |
B | 0005737 | cellular_component | cytoplasm |
B | 0005829 | cellular_component | cytosol |
B | 0006729 | biological_process | tetrahydrobiopterin biosynthetic process |
B | 0006730 | biological_process | one-carbon metabolic process |
B | 0008270 | molecular_function | zinc ion binding |
B | 0008616 | biological_process | queuosine biosynthetic process |
B | 0016787 | molecular_function | hydrolase activity |
B | 0032991 | cellular_component | protein-containing complex |
B | 0042802 | molecular_function | identical protein binding |
B | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
B | 0046872 | molecular_function | metal ion binding |
C | 0003934 | molecular_function | GTP cyclohydrolase I activity |
C | 0005525 | molecular_function | GTP binding |
C | 0005737 | cellular_component | cytoplasm |
C | 0005829 | cellular_component | cytosol |
C | 0006729 | biological_process | tetrahydrobiopterin biosynthetic process |
C | 0006730 | biological_process | one-carbon metabolic process |
C | 0008270 | molecular_function | zinc ion binding |
C | 0008616 | biological_process | queuosine biosynthetic process |
C | 0016787 | molecular_function | hydrolase activity |
C | 0032991 | cellular_component | protein-containing complex |
C | 0042802 | molecular_function | identical protein binding |
C | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
C | 0046872 | molecular_function | metal ion binding |
D | 0003934 | molecular_function | GTP cyclohydrolase I activity |
D | 0005525 | molecular_function | GTP binding |
D | 0005737 | cellular_component | cytoplasm |
D | 0005829 | cellular_component | cytosol |
D | 0006729 | biological_process | tetrahydrobiopterin biosynthetic process |
D | 0006730 | biological_process | one-carbon metabolic process |
D | 0008270 | molecular_function | zinc ion binding |
D | 0008616 | biological_process | queuosine biosynthetic process |
D | 0016787 | molecular_function | hydrolase activity |
D | 0032991 | cellular_component | protein-containing complex |
D | 0042802 | molecular_function | identical protein binding |
D | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
D | 0046872 | molecular_function | metal ion binding |
E | 0003934 | molecular_function | GTP cyclohydrolase I activity |
E | 0005525 | molecular_function | GTP binding |
E | 0005737 | cellular_component | cytoplasm |
E | 0005829 | cellular_component | cytosol |
E | 0006729 | biological_process | tetrahydrobiopterin biosynthetic process |
E | 0006730 | biological_process | one-carbon metabolic process |
E | 0008270 | molecular_function | zinc ion binding |
E | 0008616 | biological_process | queuosine biosynthetic process |
E | 0016787 | molecular_function | hydrolase activity |
E | 0032991 | cellular_component | protein-containing complex |
E | 0042802 | molecular_function | identical protein binding |
E | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
E | 0046872 | molecular_function | metal ion binding |
F | 0003934 | molecular_function | GTP cyclohydrolase I activity |
F | 0005525 | molecular_function | GTP binding |
F | 0005737 | cellular_component | cytoplasm |
F | 0005829 | cellular_component | cytosol |
F | 0006729 | biological_process | tetrahydrobiopterin biosynthetic process |
F | 0006730 | biological_process | one-carbon metabolic process |
F | 0008270 | molecular_function | zinc ion binding |
F | 0008616 | biological_process | queuosine biosynthetic process |
F | 0016787 | molecular_function | hydrolase activity |
F | 0032991 | cellular_component | protein-containing complex |
F | 0042802 | molecular_function | identical protein binding |
F | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
F | 0046872 | molecular_function | metal ion binding |
G | 0003934 | molecular_function | GTP cyclohydrolase I activity |
G | 0005525 | molecular_function | GTP binding |
G | 0005737 | cellular_component | cytoplasm |
G | 0005829 | cellular_component | cytosol |
G | 0006729 | biological_process | tetrahydrobiopterin biosynthetic process |
G | 0006730 | biological_process | one-carbon metabolic process |
G | 0008270 | molecular_function | zinc ion binding |
G | 0008616 | biological_process | queuosine biosynthetic process |
G | 0016787 | molecular_function | hydrolase activity |
G | 0032991 | cellular_component | protein-containing complex |
G | 0042802 | molecular_function | identical protein binding |
G | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
G | 0046872 | molecular_function | metal ion binding |
H | 0003934 | molecular_function | GTP cyclohydrolase I activity |
H | 0005525 | molecular_function | GTP binding |
H | 0005737 | cellular_component | cytoplasm |
H | 0005829 | cellular_component | cytosol |
H | 0006729 | biological_process | tetrahydrobiopterin biosynthetic process |
H | 0006730 | biological_process | one-carbon metabolic process |
H | 0008270 | molecular_function | zinc ion binding |
H | 0008616 | biological_process | queuosine biosynthetic process |
H | 0016787 | molecular_function | hydrolase activity |
H | 0032991 | cellular_component | protein-containing complex |
H | 0042802 | molecular_function | identical protein binding |
H | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
H | 0046872 | molecular_function | metal ion binding |
I | 0003934 | molecular_function | GTP cyclohydrolase I activity |
I | 0005525 | molecular_function | GTP binding |
I | 0005737 | cellular_component | cytoplasm |
I | 0005829 | cellular_component | cytosol |
I | 0006729 | biological_process | tetrahydrobiopterin biosynthetic process |
I | 0006730 | biological_process | one-carbon metabolic process |
I | 0008270 | molecular_function | zinc ion binding |
I | 0008616 | biological_process | queuosine biosynthetic process |
I | 0016787 | molecular_function | hydrolase activity |
I | 0032991 | cellular_component | protein-containing complex |
I | 0042802 | molecular_function | identical protein binding |
I | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
I | 0046872 | molecular_function | metal ion binding |
J | 0003934 | molecular_function | GTP cyclohydrolase I activity |
J | 0005525 | molecular_function | GTP binding |
J | 0005737 | cellular_component | cytoplasm |
J | 0005829 | cellular_component | cytosol |
J | 0006729 | biological_process | tetrahydrobiopterin biosynthetic process |
J | 0006730 | biological_process | one-carbon metabolic process |
J | 0008270 | molecular_function | zinc ion binding |
J | 0008616 | biological_process | queuosine biosynthetic process |
J | 0016787 | molecular_function | hydrolase activity |
J | 0032991 | cellular_component | protein-containing complex |
J | 0042802 | molecular_function | identical protein binding |
J | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
J | 0046872 | molecular_function | metal ion binding |
K | 0003934 | molecular_function | GTP cyclohydrolase I activity |
K | 0005525 | molecular_function | GTP binding |
K | 0005737 | cellular_component | cytoplasm |
K | 0005829 | cellular_component | cytosol |
K | 0006729 | biological_process | tetrahydrobiopterin biosynthetic process |
K | 0006730 | biological_process | one-carbon metabolic process |
K | 0008270 | molecular_function | zinc ion binding |
K | 0008616 | biological_process | queuosine biosynthetic process |
K | 0016787 | molecular_function | hydrolase activity |
K | 0032991 | cellular_component | protein-containing complex |
K | 0042802 | molecular_function | identical protein binding |
K | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
K | 0046872 | molecular_function | metal ion binding |
L | 0003934 | molecular_function | GTP cyclohydrolase I activity |
L | 0005525 | molecular_function | GTP binding |
L | 0005737 | cellular_component | cytoplasm |
L | 0005829 | cellular_component | cytosol |
L | 0006729 | biological_process | tetrahydrobiopterin biosynthetic process |
L | 0006730 | biological_process | one-carbon metabolic process |
L | 0008270 | molecular_function | zinc ion binding |
L | 0008616 | biological_process | queuosine biosynthetic process |
L | 0016787 | molecular_function | hydrolase activity |
L | 0032991 | cellular_component | protein-containing complex |
L | 0042802 | molecular_function | identical protein binding |
L | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
L | 0046872 | molecular_function | metal ion binding |
M | 0003934 | molecular_function | GTP cyclohydrolase I activity |
M | 0005525 | molecular_function | GTP binding |
M | 0005737 | cellular_component | cytoplasm |
M | 0005829 | cellular_component | cytosol |
M | 0006729 | biological_process | tetrahydrobiopterin biosynthetic process |
M | 0006730 | biological_process | one-carbon metabolic process |
M | 0008270 | molecular_function | zinc ion binding |
M | 0008616 | biological_process | queuosine biosynthetic process |
M | 0016787 | molecular_function | hydrolase activity |
M | 0032991 | cellular_component | protein-containing complex |
M | 0042802 | molecular_function | identical protein binding |
M | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
M | 0046872 | molecular_function | metal ion binding |
N | 0003934 | molecular_function | GTP cyclohydrolase I activity |
N | 0005525 | molecular_function | GTP binding |
N | 0005737 | cellular_component | cytoplasm |
N | 0005829 | cellular_component | cytosol |
N | 0006729 | biological_process | tetrahydrobiopterin biosynthetic process |
N | 0006730 | biological_process | one-carbon metabolic process |
N | 0008270 | molecular_function | zinc ion binding |
N | 0008616 | biological_process | queuosine biosynthetic process |
N | 0016787 | molecular_function | hydrolase activity |
N | 0032991 | cellular_component | protein-containing complex |
N | 0042802 | molecular_function | identical protein binding |
N | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
N | 0046872 | molecular_function | metal ion binding |
O | 0003934 | molecular_function | GTP cyclohydrolase I activity |
O | 0005525 | molecular_function | GTP binding |
O | 0005737 | cellular_component | cytoplasm |
O | 0005829 | cellular_component | cytosol |
O | 0006729 | biological_process | tetrahydrobiopterin biosynthetic process |
O | 0006730 | biological_process | one-carbon metabolic process |
O | 0008270 | molecular_function | zinc ion binding |
O | 0008616 | biological_process | queuosine biosynthetic process |
O | 0016787 | molecular_function | hydrolase activity |
O | 0032991 | cellular_component | protein-containing complex |
O | 0042802 | molecular_function | identical protein binding |
O | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
O | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 17 |
Details | BINDING SITE FOR RESIDUE GTP G 411 |
Chain | Residue |
F | CYS110 |
G | VAL131 |
G | ILE132 |
G | GLY133 |
G | LEU134 |
G | SER135 |
G | LYS136 |
G | ARG139 |
M | ARG65 |
F | HIS112 |
F | HIS113 |
F | VAL150 |
F | GLN151 |
F | GLU152 |
F | HIS179 |
F | ARG185 |
G | THR87 |
site_id | AC2 |
Number of Residues | 16 |
Details | BINDING SITE FOR RESIDUE GTP H 412 |
Chain | Residue |
G | CYS110 |
G | HIS112 |
G | HIS113 |
G | VAL150 |
G | GLN151 |
G | GLU152 |
G | HIS179 |
G | ARG185 |
H | THR87 |
H | ILE132 |
H | GLY133 |
H | LEU134 |
H | SER135 |
H | LYS136 |
H | ARG139 |
L | ARG65 |
site_id | AC3 |
Number of Residues | 16 |
Details | BINDING SITE FOR RESIDUE GTP I 413 |
Chain | Residue |
H | HIS112 |
H | HIS113 |
H | VAL150 |
H | GLN151 |
H | GLU152 |
H | HIS179 |
H | ARG185 |
I | THR87 |
I | VAL131 |
I | ILE132 |
I | GLY133 |
I | LEU134 |
I | SER135 |
I | LYS136 |
I | ARG139 |
K | ARG65 |
site_id | AC4 |
Number of Residues | 17 |
Details | BINDING SITE FOR RESIDUE GTP J 414 |
Chain | Residue |
I | CYS110 |
I | HIS112 |
I | HIS113 |
I | VAL150 |
I | GLN151 |
I | GLU152 |
I | HIS179 |
I | ARG185 |
J | THR87 |
J | ILE132 |
J | GLY133 |
J | LEU134 |
J | SER135 |
J | LYS136 |
J | ARG139 |
O | ARG65 |
O | LYS68 |
site_id | AC5 |
Number of Residues | 17 |
Details | BINDING SITE FOR RESIDUE GTP F 415 |
Chain | Residue |
F | THR87 |
F | ILE132 |
F | GLY133 |
F | LEU134 |
F | SER135 |
F | LYS136 |
F | ARG139 |
J | CYS110 |
J | HIS112 |
J | HIS113 |
J | VAL150 |
J | GLN151 |
J | GLU152 |
J | HIS179 |
J | ARG185 |
J | ILE187 |
N | ARG65 |
site_id | AC6 |
Number of Residues | 16 |
Details | BINDING SITE FOR RESIDUE GTP L 416 |
Chain | Residue |
H | ARG65 |
K | HIS112 |
K | HIS113 |
K | VAL150 |
K | GLN151 |
K | GLU152 |
K | HIS179 |
K | ARG185 |
L | THR87 |
L | VAL131 |
L | ILE132 |
L | GLY133 |
L | LEU134 |
L | SER135 |
L | LYS136 |
L | ARG139 |
site_id | AC7 |
Number of Residues | 16 |
Details | BINDING SITE FOR RESIDUE GTP M 417 |
Chain | Residue |
G | ARG65 |
L | HIS112 |
L | HIS113 |
L | VAL150 |
L | GLN151 |
L | GLU152 |
L | HIS179 |
L | ARG185 |
M | THR87 |
M | VAL131 |
M | ILE132 |
M | GLY133 |
M | LEU134 |
M | SER135 |
M | LYS136 |
M | ARG139 |
site_id | AC8 |
Number of Residues | 17 |
Details | BINDING SITE FOR RESIDUE GTP N 418 |
Chain | Residue |
F | ARG65 |
M | CYS110 |
M | HIS112 |
M | HIS113 |
M | VAL150 |
M | GLN151 |
M | GLU152 |
M | HIS179 |
M | VAL182 |
M | ARG185 |
N | THR87 |
N | ILE132 |
N | GLY133 |
N | LEU134 |
N | SER135 |
N | LYS136 |
N | ARG139 |
site_id | AC9 |
Number of Residues | 15 |
Details | BINDING SITE FOR RESIDUE GTP O 419 |
Chain | Residue |
J | ARG65 |
N | HIS112 |
N | HIS113 |
N | VAL150 |
N | GLN151 |
N | GLU152 |
N | HIS179 |
N | ARG185 |
O | THR87 |
O | ILE132 |
O | GLY133 |
O | LEU134 |
O | SER135 |
O | LYS136 |
O | ARG139 |
site_id | BC1 |
Number of Residues | 17 |
Details | BINDING SITE FOR RESIDUE GTP K 420 |
Chain | Residue |
I | ARG65 |
I | LYS68 |
K | THR87 |
K | ILE132 |
K | GLY133 |
K | LEU134 |
K | SER135 |
K | LYS136 |
K | ARG139 |
O | CYS110 |
O | HIS112 |
O | HIS113 |
O | VAL150 |
O | GLN151 |
O | GLU152 |
O | HIS179 |
O | ARG185 |
site_id | BC2 |
Number of Residues | 16 |
Details | BINDING SITE FOR RESIDUE GTP B 421 |
Chain | Residue |
A | HIS112 |
A | HIS113 |
A | VAL150 |
A | GLN151 |
A | GLU152 |
A | HIS179 |
A | ARG185 |
B | THR87 |
B | VAL131 |
B | ILE132 |
B | GLY133 |
B | LEU134 |
B | SER135 |
B | LYS136 |
B | ARG139 |
E | ARG65 |
site_id | BC3 |
Number of Residues | 16 |
Details | BINDING SITE FOR RESIDUE GTP C 422 |
Chain | Residue |
B | HIS112 |
B | HIS113 |
B | VAL150 |
B | GLN151 |
B | GLU152 |
B | HIS179 |
B | ARG185 |
C | THR87 |
C | VAL131 |
C | ILE132 |
C | GLY133 |
C | LEU134 |
C | SER135 |
C | LYS136 |
C | ARG139 |
D | ARG65 |
site_id | BC4 |
Number of Residues | 17 |
Details | BINDING SITE FOR RESIDUE GTP D 423 |
Chain | Residue |
C | ARG65 |
C | CYS110 |
C | HIS112 |
C | HIS113 |
C | VAL150 |
C | GLN151 |
C | GLU152 |
C | HIS179 |
C | VAL182 |
C | ARG185 |
D | THR87 |
D | ILE132 |
D | GLY133 |
D | LEU134 |
D | SER135 |
D | LYS136 |
D | ARG139 |
site_id | BC5 |
Number of Residues | 16 |
Details | BINDING SITE FOR RESIDUE GTP E 424 |
Chain | Residue |
B | ARG65 |
D | HIS112 |
D | HIS113 |
D | VAL150 |
D | GLN151 |
D | GLU152 |
D | HIS179 |
D | ARG185 |
E | THR87 |
E | VAL131 |
E | ILE132 |
E | GLY133 |
E | LEU134 |
E | SER135 |
E | LYS136 |
E | ARG139 |
site_id | BC6 |
Number of Residues | 15 |
Details | BINDING SITE FOR RESIDUE GTP A 425 |
Chain | Residue |
A | ARG65 |
A | THR87 |
A | ILE132 |
A | GLY133 |
A | LEU134 |
A | SER135 |
A | LYS136 |
A | ARG139 |
E | HIS112 |
E | HIS113 |
E | VAL150 |
E | GLN151 |
E | GLU152 |
E | HIS179 |
E | ARG185 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 45 |
Details | BINDING: |
Chain | Residue | Details |
F | GLU111 | |
I | GLU111 | |
I | PHE114 | |
I | VAL182 | |
J | GLU111 | |
J | PHE114 | |
J | VAL182 | |
K | GLU111 | |
K | PHE114 | |
K | VAL182 | |
L | GLU111 | |
F | PHE114 | |
L | PHE114 | |
L | VAL182 | |
M | GLU111 | |
M | PHE114 | |
M | VAL182 | |
N | GLU111 | |
N | PHE114 | |
N | VAL182 | |
O | GLU111 | |
O | PHE114 | |
F | VAL182 | |
O | VAL182 | |
A | GLU111 | |
A | PHE114 | |
A | VAL182 | |
B | GLU111 | |
B | PHE114 | |
B | VAL182 | |
C | GLU111 | |
C | PHE114 | |
C | VAL182 | |
G | GLU111 | |
D | GLU111 | |
D | PHE114 | |
D | VAL182 | |
E | GLU111 | |
E | PHE114 | |
E | VAL182 | |
G | PHE114 | |
G | VAL182 | |
H | GLU111 | |
H | PHE114 | |
H | VAL182 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1gtp |
Chain | Residue | Details |
F | HIS179 | |
F | HIS112 |
site_id | CSA10 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1gtp |
Chain | Residue | Details |
O | HIS179 | |
O | HIS112 |
site_id | CSA11 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1gtp |
Chain | Residue | Details |
A | HIS179 | |
A | HIS112 |
site_id | CSA12 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1gtp |
Chain | Residue | Details |
B | HIS179 | |
B | HIS112 |
site_id | CSA13 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1gtp |
Chain | Residue | Details |
C | HIS179 | |
C | HIS112 |
site_id | CSA14 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1gtp |
Chain | Residue | Details |
D | HIS179 | |
D | HIS112 |
site_id | CSA15 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1gtp |
Chain | Residue | Details |
E | HIS179 | |
E | HIS112 |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1gtp |
Chain | Residue | Details |
G | HIS179 | |
G | HIS112 |
site_id | CSA3 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1gtp |
Chain | Residue | Details |
H | HIS179 | |
H | HIS112 |
site_id | CSA4 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1gtp |
Chain | Residue | Details |
I | HIS179 | |
I | HIS112 |
site_id | CSA5 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1gtp |
Chain | Residue | Details |
J | HIS179 | |
J | HIS112 |
site_id | CSA6 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1gtp |
Chain | Residue | Details |
K | HIS179 | |
K | HIS112 |
site_id | CSA7 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1gtp |
Chain | Residue | Details |
L | HIS179 | |
L | HIS112 |
site_id | CSA8 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1gtp |
Chain | Residue | Details |
M | HIS179 | |
M | HIS112 |
site_id | CSA9 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1gtp |
Chain | Residue | Details |
N | HIS179 | |
N | HIS112 |
site_id | MCSA1 |
Number of Residues | 7 |
Details | M-CSA 38 |
Chain | Residue | Details |
F | GLU111 | metal ligand |
F | HIS112 | electrostatic stabiliser, hydrogen bond acceptor |
F | HIS113 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
F | PHE114 | metal ligand |
F | GLU152 | electrostatic stabiliser, hydrogen bond acceptor |
F | TYR180 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
F | VAL182 | metal ligand |
site_id | MCSA10 |
Number of Residues | 7 |
Details | M-CSA 38 |
Chain | Residue | Details |
O | GLU111 | metal ligand |
O | HIS112 | electrostatic stabiliser, hydrogen bond acceptor |
O | HIS113 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
O | PHE114 | metal ligand |
O | GLU152 | electrostatic stabiliser, hydrogen bond acceptor |
O | TYR180 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
O | VAL182 | metal ligand |
site_id | MCSA11 |
Number of Residues | 7 |
Details | M-CSA 38 |
Chain | Residue | Details |
A | GLU111 | metal ligand |
A | HIS112 | electrostatic stabiliser, hydrogen bond acceptor |
A | HIS113 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
A | PHE114 | metal ligand |
A | GLU152 | electrostatic stabiliser, hydrogen bond acceptor |
A | TYR180 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
A | VAL182 | metal ligand |
site_id | MCSA12 |
Number of Residues | 7 |
Details | M-CSA 38 |
Chain | Residue | Details |
B | GLU111 | metal ligand |
B | HIS112 | electrostatic stabiliser, hydrogen bond acceptor |
B | HIS113 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
B | PHE114 | metal ligand |
B | GLU152 | electrostatic stabiliser, hydrogen bond acceptor |
B | TYR180 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
B | VAL182 | metal ligand |
site_id | MCSA13 |
Number of Residues | 7 |
Details | M-CSA 38 |
Chain | Residue | Details |
C | GLU111 | metal ligand |
C | HIS112 | electrostatic stabiliser, hydrogen bond acceptor |
C | HIS113 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
C | PHE114 | metal ligand |
C | GLU152 | electrostatic stabiliser, hydrogen bond acceptor |
C | TYR180 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
C | VAL182 | metal ligand |
site_id | MCSA14 |
Number of Residues | 7 |
Details | M-CSA 38 |
Chain | Residue | Details |
D | GLU111 | metal ligand |
D | HIS112 | electrostatic stabiliser, hydrogen bond acceptor |
D | HIS113 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
D | PHE114 | metal ligand |
D | GLU152 | electrostatic stabiliser, hydrogen bond acceptor |
D | TYR180 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
D | VAL182 | metal ligand |
site_id | MCSA15 |
Number of Residues | 7 |
Details | M-CSA 38 |
Chain | Residue | Details |
E | GLU111 | metal ligand |
E | HIS112 | electrostatic stabiliser, hydrogen bond acceptor |
E | HIS113 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
E | PHE114 | metal ligand |
E | GLU152 | electrostatic stabiliser, hydrogen bond acceptor |
E | TYR180 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
E | VAL182 | metal ligand |
site_id | MCSA2 |
Number of Residues | 7 |
Details | M-CSA 38 |
Chain | Residue | Details |
G | GLU111 | metal ligand |
G | HIS112 | electrostatic stabiliser, hydrogen bond acceptor |
G | HIS113 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
G | PHE114 | metal ligand |
G | GLU152 | electrostatic stabiliser, hydrogen bond acceptor |
G | TYR180 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
G | VAL182 | metal ligand |
site_id | MCSA3 |
Number of Residues | 7 |
Details | M-CSA 38 |
Chain | Residue | Details |
H | GLU111 | metal ligand |
H | HIS112 | electrostatic stabiliser, hydrogen bond acceptor |
H | HIS113 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
H | PHE114 | metal ligand |
H | GLU152 | electrostatic stabiliser, hydrogen bond acceptor |
H | TYR180 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
H | VAL182 | metal ligand |
site_id | MCSA4 |
Number of Residues | 7 |
Details | M-CSA 38 |
Chain | Residue | Details |
I | GLU111 | metal ligand |
I | HIS112 | electrostatic stabiliser, hydrogen bond acceptor |
I | HIS113 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
I | PHE114 | metal ligand |
I | GLU152 | electrostatic stabiliser, hydrogen bond acceptor |
I | TYR180 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
I | VAL182 | metal ligand |
site_id | MCSA5 |
Number of Residues | 7 |
Details | M-CSA 38 |
Chain | Residue | Details |
J | GLU111 | metal ligand |
J | HIS112 | electrostatic stabiliser, hydrogen bond acceptor |
J | HIS113 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
J | PHE114 | metal ligand |
J | GLU152 | electrostatic stabiliser, hydrogen bond acceptor |
J | TYR180 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
J | VAL182 | metal ligand |
site_id | MCSA6 |
Number of Residues | 7 |
Details | M-CSA 38 |
Chain | Residue | Details |
K | GLU111 | metal ligand |
K | HIS112 | electrostatic stabiliser, hydrogen bond acceptor |
K | HIS113 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
K | PHE114 | metal ligand |
K | GLU152 | electrostatic stabiliser, hydrogen bond acceptor |
K | TYR180 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
K | VAL182 | metal ligand |
site_id | MCSA7 |
Number of Residues | 7 |
Details | M-CSA 38 |
Chain | Residue | Details |
L | GLU111 | metal ligand |
L | HIS112 | electrostatic stabiliser, hydrogen bond acceptor |
L | HIS113 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
L | PHE114 | metal ligand |
L | GLU152 | electrostatic stabiliser, hydrogen bond acceptor |
L | TYR180 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
L | VAL182 | metal ligand |
site_id | MCSA8 |
Number of Residues | 7 |
Details | M-CSA 38 |
Chain | Residue | Details |
M | GLU111 | metal ligand |
M | HIS112 | electrostatic stabiliser, hydrogen bond acceptor |
M | HIS113 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
M | PHE114 | metal ligand |
M | GLU152 | electrostatic stabiliser, hydrogen bond acceptor |
M | TYR180 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
M | VAL182 | metal ligand |
site_id | MCSA9 |
Number of Residues | 7 |
Details | M-CSA 38 |
Chain | Residue | Details |
N | GLU111 | metal ligand |
N | HIS112 | electrostatic stabiliser, hydrogen bond acceptor |
N | HIS113 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
N | PHE114 | metal ligand |
N | GLU152 | electrostatic stabiliser, hydrogen bond acceptor |
N | TYR180 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
N | VAL182 | metal ligand |