Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0030234 | molecular_function | enzyme regulator activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0005509 | molecular_function | calcium ion binding |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0030234 | molecular_function | enzyme regulator activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PB A 500 |
| Chain | Residue |
| A | ASP58 |
| A | ASP64 |
| A | GLU67 |
| B | GLU114 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PB A 501 |
| Chain | Residue |
| A | GLU67 |
| A | ASP56 |
| A | ASP58 |
| A | ASN60 |
| A | THR62 |
| A | ASP64 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PB A 502 |
| Chain | Residue |
| A | GLU7 |
| A | ASP58 |
| B | GLU114 |
| B | LYS115 |
| B | GLU120 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PB A 503 |
| Chain | Residue |
| A | ASP20 |
| A | ASP22 |
| A | ASP24 |
| A | THR26 |
| A | GLU31 |
| A | HOH1006 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PB A 504 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PB B 505 |
| Chain | Residue |
| A | GLU2 |
| A | HOH1031 |
| B | GLU84 |
| B | GLU87 |
| B | GLU123 |
| B | HOH2052 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PB B 506 |
| Chain | Residue |
| A | CAC1001 |
| B | ASP80 |
| B | GLU83 |
| B | GLU127 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PB A 507 |
| Chain | Residue |
| A | GLU2 |
| A | CAC1001 |
| A | HOH1020 |
| B | GLU83 |
| B | GLU84 |
| B | GLU123 |
| B | GLU127 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PB B 508 |
| Chain | Residue |
| B | ASP129 |
| B | ASP131 |
| B | ASP133 |
| B | HIS135 |
| B | GLU140 |
| B | HOH2027 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PB B 509 |
| Chain | Residue |
| A | CAC1001 |
| B | ASP80 |
| B | HOH2041 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PB B 510 |
| Chain | Residue |
| B | ASP93 |
| B | ASP95 |
| B | ASN97 |
| B | LEU99 |
| B | GLU104 |
| B | HOH2050 |
| site_id | BC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE CAC A 1001 |
| Chain | Residue |
| A | ALA1 |
| A | GLU2 |
| A | PB507 |
| A | HOH1020 |
| A | HOH1034 |
| B | ASP80 |
| B | GLU83 |
| B | GLU127 |
| B | PB506 |
| B | PB509 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT B 2001 |
| Chain | Residue |
| B | VAL108 |
| B | ASN111 |
| B | LEU112 |
Functional Information from PROSITE/UniProt
| site_id | PS00018 |
| Number of Residues | 13 |
| Details | EF_HAND_1 EF-hand calcium-binding domain. DKDGDGTITtkEL |
| Chain | Residue | Details |
| A | ASP20-LEU32 | |
| A | ASP56-PHE68 | |
| A | ASP93-LEU105 | |
| A | ASP129-PHE141 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 35 |
| Details | Domain: {"description":"EF-hand 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 35 |
| Details | Domain: {"description":"EF-hand 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 19 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N-acetylalanine","evidences":[{"source":"PubMed","id":"3100523","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6,N6-dimethyllysine","evidences":[{"source":"PubMed","id":"3100523","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 35 |
| Details | Domain: {"description":"EF-hand 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N6,N6,N6-trimethyllysine","evidences":[{"source":"PubMed","id":"3100523","evidenceCode":"ECO:0000269"}]} |
