Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004798 | molecular_function | dTMP kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005525 | molecular_function | GTP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006227 | biological_process | dUDP biosynthetic process |
| A | 0006233 | biological_process | dTDP biosynthetic process |
| A | 0006235 | biological_process | dTTP biosynthetic process |
| A | 0009165 | biological_process | nucleotide biosynthetic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0046044 | biological_process | TMP metabolic process |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 A 219 |
| Chain | Residue |
| A | GLN121 |
| A | HOH311 |
| A | LYS132 |
| A | ALA154 |
| A | GLN155 |
| A | ALA161 |
| A | ARG162 |
| A | ARG167 |
| A | TRP187 |
| A | GLY188 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 220 |
| Chain | Residue |
| A | GLY10 |
| A | ALA11 |
| A | GLY12 |
| A | LYS13 |
| A | ARG14 |
| A | ARG153 |
| A | HOH306 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG A 300 |
| Chain | Residue |
| A | ASP9 |
| A | GLU166 |
| A | T5A301 |
| site_id | AC4 |
| Number of Residues | 27 |
| Details | BINDING SITE FOR RESIDUE T5A A 301 |
| Chain | Residue |
| A | ASP9 |
| A | PRO37 |
| A | TYR39 |
| A | ALA49 |
| A | GLU50 |
| A | HIS53 |
| A | GLU55 |
| A | PHE70 |
| A | ARG74 |
| A | ARG95 |
| A | SER99 |
| A | ASN100 |
| A | TYR103 |
| A | ARG122 |
| A | ARG160 |
| A | ASP163 |
| A | TYR165 |
| A | GLU166 |
| A | MG300 |
| A | HOH306 |
| A | HOH309 |
| A | HOH318 |
| A | HOH328 |
| A | HOH329 |
| A | HOH331 |
| A | HOH334 |
| A | HOH359 |
Functional Information from PROSITE/UniProt
| site_id | PS01331 |
| Number of Residues | 13 |
| Details | THYMIDYLATE_KINASE Thymidylate kinase signature. ILDRYvaSNaAYS |
| Chain | Residue | Details |
| A | ILE92-SER104 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | Region: {"description":"LID"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 17 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Site: {"description":"Transition state stabilizer","evidences":[{"evidenceCode":"ECO:0000255"}]} |
