1MOQ
ISOMERASE DOMAIN OF GLUCOSAMINE 6-PHOSPHATE SYNTHASE COMPLEXED WITH GLUCOSAMINE 6-PHOSPHATE
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004360 | molecular_function | glutamine-fructose-6-phosphate transaminase (isomerizing) activity |
| A | 0097367 | molecular_function | carbohydrate derivative binding |
| A | 1901135 | biological_process | carbohydrate derivative metabolic process |
| A | 1901137 | biological_process | carbohydrate derivative biosynthetic process |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 140 |
| Details | Domain: {"description":"SIS 1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 141 |
| Details | Domain: {"description":"SIS 2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Active site: {"description":"For Fru-6P isomerization activity"} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | a catalytic site defined by CSA, PubMed 7932726, 10091662 |
| Chain | Residue | Details |
| A | LYS603 | |
| A | LYS485 | |
| A | GLU488 | |
| A | GLU481 |
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 82 |
| Chain | Residue | Details |
| A | GLU481 | electrostatic stabiliser, hydrogen bond acceptor |
| A | LYS485 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | GLU488 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | HIS504 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | LYS603 | covalently attached, electron pair acceptor, electron pair donor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor |
