1MLC

MONOCLONAL ANTIBODY FAB D44.1 RAISED AGAINST CHICKEN EGG-WHITE LYSOZYME COMPLEXED WITH LYSOZYME

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0005886	cellular_component	plasma membrane
A	0030183	biological_process	B cell differentiation
C	0005576	cellular_component	extracellular region
C	0005886	cellular_component	plasma membrane
C	0030183	biological_process	B cell differentiation
E	0003796	molecular_function	lysozyme activity
E	0005515	molecular_function	protein binding
E	0005576	cellular_component	extracellular region
E	0005615	cellular_component	extracellular space
E	0005737	cellular_component	cytoplasm
E	0005783	cellular_component	endoplasmic reticulum
E	0016231	molecular_function	beta-N-acetylglucosaminidase activity
E	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
E	0016998	biological_process	cell wall macromolecule catabolic process
E	0031640	biological_process	killing of cells of another organism
E	0042742	biological_process	defense response to bacterium
E	0042802	molecular_function	identical protein binding
E	0050829	biological_process	defense response to Gram-negative bacterium
E	0050830	biological_process	defense response to Gram-positive bacterium
E	0051672	biological_process	obsolete catabolism by organism of cell wall peptidoglycan in other organism
F	0003796	molecular_function	lysozyme activity
F	0005515	molecular_function	protein binding
F	0005576	cellular_component	extracellular region
F	0005615	cellular_component	extracellular space
F	0005737	cellular_component	cytoplasm
F	0005783	cellular_component	endoplasmic reticulum
F	0016231	molecular_function	beta-N-acetylglucosaminidase activity
F	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
F	0016998	biological_process	cell wall macromolecule catabolic process
F	0031640	biological_process	killing of cells of another organism
F	0042742	biological_process	defense response to bacterium
F	0042802	molecular_function	identical protein binding
F	0050829	biological_process	defense response to Gram-negative bacterium
F	0050830	biological_process	defense response to Gram-positive bacterium
F	0051672	biological_process	obsolete catabolism by organism of cell wall peptidoglycan in other organism

Functional Information from PROSITE/UniProt

site_id	PS00128
Number of Residues	19
Details	GLYCOSYL_HYDROL_F22_1 Glycosyl hydrolases family 22 (GH22) domain signature. CnipCsaLlssDItasvnC

Chain	Residue	Details
E	CYS76-CYS94

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site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH

Chain	Residue	Details
A	TYR192-HIS198

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE:

Chain	Residue	Details
E	GLU35
E	ASP52
F	GLU35
F	ASP52

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING:

Chain	Residue	Details
E	ASP101
F	ASP101

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 132l

Chain	Residue	Details
E	GLU35
E	ASP52

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site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 132l

Chain	Residue	Details
F	GLU35
F	ASP52

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site_id	MCSA1
Number of Residues	6
Details	M-CSA 203

Chain	Residue	Details
E	GLU35	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
E	ASN46
E	ASP48
E	SER50
E	ASP52	covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction
E	ASN59

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site_id	MCSA2
Number of Residues	6
Details	M-CSA 203

Chain	Residue	Details
F	GLU35	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
F	ASN46
F	ASP48
F	SER50
F	ASP52	covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction
F	ASN59

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