1ML7

Crystal structure of nitrophorin 4 complexed with 4-iodopyrazole

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0016491	molecular_function	oxidoreductase activity
A	0042311	biological_process	vasodilation
A	0046872	molecular_function	metal ion binding
A	0051381	molecular_function	histamine binding
A	0070026	molecular_function	nitric oxide binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	19
Details	BINDING SITE FOR RESIDUE HEV A 185

Chain	Residue
A	VAL25
A	LYS88
A	TYR105
A	PHE107
A	LEU123
A	LYS125
A	LYS128
A	LEU133
A	PYZ186
A	HOH215
A	HOH444
A	TYR28
A	VAL36
A	TYR40
A	LEU44
A	LEU57
A	HIS59
A	ASP70
A	PHE86

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PYZ A 186

Chain	Residue
A	ASP35
A	LEU123
A	GLY131
A	LEU133
A	HEV185
A	HOH408

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site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PYZ A 187

Chain	Residue
A	ASN85
A	ALA101
A	GLY102
A	TYR104
A	TYR104

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING: proximal binding residue => ECO:0000269|PubMed:10876239, ECO:0000269|PubMed:11560480, ECO:0000269|PubMed:14673714, ECO:0000269|PubMed:16171383, ECO:0000269|PubMed:20524697, ECO:0000269|PubMed:22334402, ECO:0000269|PubMed:22976968, ECO:0000269|PubMed:23474537, ECO:0000269|PubMed:9782054

Chain	Residue	Details
A	HIS59

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