1MKB
ESCHERICHIA COLI BETA-HYDROXYDECANOYL THIOL ESTER DEHYDRASE AT PH 5 AND 21 DEGREES C
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006631 | biological_process | fatty acid metabolic process |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| A | 0006636 | biological_process | unsaturated fatty acid biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0019171 | molecular_function | (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity |
| A | 0034017 | molecular_function | trans-2-decenoyl-acyl-carrier-protein isomerase activity |
| A | 0042803 | molecular_function | protein homodimerization activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0006631 | biological_process | fatty acid metabolic process |
| B | 0006633 | biological_process | fatty acid biosynthetic process |
| B | 0006636 | biological_process | unsaturated fatty acid biosynthetic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0019171 | molecular_function | (3R)-hydroxyacyl-[acyl-carrier-protein] dehydratase activity |
| B | 0034017 | molecular_function | trans-2-decenoyl-acyl-carrier-protein isomerase activity |
| B | 0042803 | molecular_function | protein homodimerization activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | TWO POLAR RESIDUES ARE FOUND IN THE CATALYTIC REGION OF THE ACTIVE SITE. |
| Chain | Residue |
| A | HIS70 |
| B | ASP84 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | TWO POLAR RESIDUES ARE FOUND IN THE CATALYTIC REGION OF THE ACTIVE SITE. |
| Chain | Residue |
| B | HIS70 |
| A | ASP84 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"21276098","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1mka |
| Chain | Residue | Details |
| A | ASP84 | |
| B | CYS80 | |
| B | VAL76 | |
| B | GLY79 | |
| B | HIS70 |
| site_id | CSA2 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1mka |
| Chain | Residue | Details |
| A | CYS80 | |
| A | VAL76 | |
| A | GLY79 | |
| A | HIS70 | |
| B | ASP84 |
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 10 |
| Chain | Residue | Details |
| A | HIS70 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | VAL76 | activator, electrostatic stabiliser, hydrogen bond acceptor |
| A | GLY79 | electrostatic stabiliser, hydrogen bond donor |
| A | CYS80 | electrostatic stabiliser, hydrogen bond donor |
| A | ASP84 | hydrogen bond donor, proton acceptor, proton donor |
| site_id | MCSA2 |
| Number of Residues | 5 |
| Details | M-CSA 10 |
| Chain | Residue | Details |
| B | HIS70 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| B | VAL76 | activator, electrostatic stabiliser, hydrogen bond acceptor |
| B | GLY79 | electrostatic stabiliser, hydrogen bond donor |
| B | CYS80 | electrostatic stabiliser, hydrogen bond donor |
| B | ASP84 | hydrogen bond donor, proton acceptor, proton donor |
