Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003908 | molecular_function | methylated-DNA-[protein]-cysteine S-methyltransferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006281 | biological_process | DNA repair |
| A | 0006307 | biological_process | DNA alkylation repair |
| A | 0006974 | biological_process | DNA damage response |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0032259 | biological_process | methylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 301 |
| Chain | Residue |
| A | ARG8 |
| A | THR111 |
| A | TYR112 |
| A | GLY113 |
| A | ALA146 |
| A | HIS147 |
| A | HOH539 |
| A | HOH540 |
| A | HOH600 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 302 |
| Chain | Residue |
| A | LYS6 |
| A | ARG8 |
| A | ARG124 |
| A | HOH547 |
| A | HOH621 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 303 |
| Chain | Residue |
| A | HIS46 |
| A | ARG50 |
| A | ASN120 |
| A | ARG132 |
Functional Information from PROSITE/UniProt
| site_id | PS00374 |
| Number of Residues | 7 |
| Details | MGMT Methylated-DNA--protein-cysteine methyltransferase active site. VPCHRVV |
| Chain | Residue | Details |
| A | VAL139-VAL145 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Nucleophile; methyl group acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_00772","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"10497033","evidenceCode":"ECO:0000305"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1eh6 |
| Chain | Residue | Details |
| A | HIS142 | |
| A | ASN133 | |
| A | CYS141 | |
| A | GLU167 | |
