Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1MFR

CRYSTAL STRUCTURE OF M FERRITIN

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004322	molecular_function	ferroxidase activity
A	0005737	cellular_component	cytoplasm
A	0006826	biological_process	iron ion transport
A	0006879	biological_process	intracellular iron ion homeostasis
A	0008198	molecular_function	ferrous iron binding
A	0008199	molecular_function	ferric iron binding
A	0016491	molecular_function	oxidoreductase activity
A	0046872	molecular_function	metal ion binding
B	0004322	molecular_function	ferroxidase activity
B	0005737	cellular_component	cytoplasm
B	0006826	biological_process	iron ion transport
B	0006879	biological_process	intracellular iron ion homeostasis
B	0008198	molecular_function	ferrous iron binding
B	0008199	molecular_function	ferric iron binding
B	0016491	molecular_function	oxidoreductase activity
B	0046872	molecular_function	metal ion binding
C	0004322	molecular_function	ferroxidase activity
C	0005737	cellular_component	cytoplasm
C	0006826	biological_process	iron ion transport
C	0006879	biological_process	intracellular iron ion homeostasis
C	0008198	molecular_function	ferrous iron binding
C	0008199	molecular_function	ferric iron binding
C	0016491	molecular_function	oxidoreductase activity
C	0046872	molecular_function	metal ion binding
D	0004322	molecular_function	ferroxidase activity
D	0005737	cellular_component	cytoplasm
D	0006826	biological_process	iron ion transport
D	0006879	biological_process	intracellular iron ion homeostasis
D	0008198	molecular_function	ferrous iron binding
D	0008199	molecular_function	ferric iron binding
D	0016491	molecular_function	oxidoreductase activity
D	0046872	molecular_function	metal ion binding
E	0004322	molecular_function	ferroxidase activity
E	0005737	cellular_component	cytoplasm
E	0006826	biological_process	iron ion transport
E	0006879	biological_process	intracellular iron ion homeostasis
E	0008198	molecular_function	ferrous iron binding
E	0008199	molecular_function	ferric iron binding
E	0016491	molecular_function	oxidoreductase activity
E	0046872	molecular_function	metal ion binding
F	0004322	molecular_function	ferroxidase activity
F	0005737	cellular_component	cytoplasm
F	0006826	biological_process	iron ion transport
F	0006879	biological_process	intracellular iron ion homeostasis
F	0008198	molecular_function	ferrous iron binding
F	0008199	molecular_function	ferric iron binding
F	0016491	molecular_function	oxidoreductase activity
F	0046872	molecular_function	metal ion binding
G	0004322	molecular_function	ferroxidase activity
G	0005737	cellular_component	cytoplasm
G	0006826	biological_process	iron ion transport
G	0006879	biological_process	intracellular iron ion homeostasis
G	0008198	molecular_function	ferrous iron binding
G	0008199	molecular_function	ferric iron binding
G	0016491	molecular_function	oxidoreductase activity
G	0046872	molecular_function	metal ion binding
H	0004322	molecular_function	ferroxidase activity
H	0005737	cellular_component	cytoplasm
H	0006826	biological_process	iron ion transport
H	0006879	biological_process	intracellular iron ion homeostasis
H	0008198	molecular_function	ferrous iron binding
H	0008199	molecular_function	ferric iron binding
H	0016491	molecular_function	oxidoreductase activity
H	0046872	molecular_function	metal ion binding
I	0004322	molecular_function	ferroxidase activity
I	0005737	cellular_component	cytoplasm
I	0006826	biological_process	iron ion transport
I	0006879	biological_process	intracellular iron ion homeostasis
I	0008198	molecular_function	ferrous iron binding
I	0008199	molecular_function	ferric iron binding
I	0016491	molecular_function	oxidoreductase activity
I	0046872	molecular_function	metal ion binding
J	0004322	molecular_function	ferroxidase activity
J	0005737	cellular_component	cytoplasm
J	0006826	biological_process	iron ion transport
J	0006879	biological_process	intracellular iron ion homeostasis
J	0008198	molecular_function	ferrous iron binding
J	0008199	molecular_function	ferric iron binding
J	0016491	molecular_function	oxidoreductase activity
J	0046872	molecular_function	metal ion binding
K	0004322	molecular_function	ferroxidase activity
K	0005737	cellular_component	cytoplasm
K	0006826	biological_process	iron ion transport
K	0006879	biological_process	intracellular iron ion homeostasis
K	0008198	molecular_function	ferrous iron binding
K	0008199	molecular_function	ferric iron binding
K	0016491	molecular_function	oxidoreductase activity
K	0046872	molecular_function	metal ion binding
L	0004322	molecular_function	ferroxidase activity
L	0005737	cellular_component	cytoplasm
L	0006826	biological_process	iron ion transport
L	0006879	biological_process	intracellular iron ion homeostasis
L	0008198	molecular_function	ferrous iron binding
L	0008199	molecular_function	ferric iron binding
L	0016491	molecular_function	oxidoreductase activity
L	0046872	molecular_function	metal ion binding
M	0004322	molecular_function	ferroxidase activity
M	0005737	cellular_component	cytoplasm
M	0006826	biological_process	iron ion transport
M	0006879	biological_process	intracellular iron ion homeostasis
M	0008198	molecular_function	ferrous iron binding
M	0008199	molecular_function	ferric iron binding
M	0016491	molecular_function	oxidoreductase activity
M	0046872	molecular_function	metal ion binding
N	0004322	molecular_function	ferroxidase activity
N	0005737	cellular_component	cytoplasm
N	0006826	biological_process	iron ion transport
N	0006879	biological_process	intracellular iron ion homeostasis
N	0008198	molecular_function	ferrous iron binding
N	0008199	molecular_function	ferric iron binding
N	0016491	molecular_function	oxidoreductase activity
N	0046872	molecular_function	metal ion binding
O	0004322	molecular_function	ferroxidase activity
O	0005737	cellular_component	cytoplasm
O	0006826	biological_process	iron ion transport
O	0006879	biological_process	intracellular iron ion homeostasis
O	0008198	molecular_function	ferrous iron binding
O	0008199	molecular_function	ferric iron binding
O	0016491	molecular_function	oxidoreductase activity
O	0046872	molecular_function	metal ion binding
P	0004322	molecular_function	ferroxidase activity
P	0005737	cellular_component	cytoplasm
P	0006826	biological_process	iron ion transport
P	0006879	biological_process	intracellular iron ion homeostasis
P	0008198	molecular_function	ferrous iron binding
P	0008199	molecular_function	ferric iron binding
P	0016491	molecular_function	oxidoreductase activity
P	0046872	molecular_function	metal ion binding
Q	0004322	molecular_function	ferroxidase activity
Q	0005737	cellular_component	cytoplasm
Q	0006826	biological_process	iron ion transport
Q	0006879	biological_process	intracellular iron ion homeostasis
Q	0008198	molecular_function	ferrous iron binding
Q	0008199	molecular_function	ferric iron binding
Q	0016491	molecular_function	oxidoreductase activity
Q	0046872	molecular_function	metal ion binding
R	0004322	molecular_function	ferroxidase activity
R	0005737	cellular_component	cytoplasm
R	0006826	biological_process	iron ion transport
R	0006879	biological_process	intracellular iron ion homeostasis
R	0008198	molecular_function	ferrous iron binding
R	0008199	molecular_function	ferric iron binding
R	0016491	molecular_function	oxidoreductase activity
R	0046872	molecular_function	metal ion binding
S	0004322	molecular_function	ferroxidase activity
S	0005737	cellular_component	cytoplasm
S	0006826	biological_process	iron ion transport
S	0006879	biological_process	intracellular iron ion homeostasis
S	0008198	molecular_function	ferrous iron binding
S	0008199	molecular_function	ferric iron binding
S	0016491	molecular_function	oxidoreductase activity
S	0046872	molecular_function	metal ion binding
T	0004322	molecular_function	ferroxidase activity
T	0005737	cellular_component	cytoplasm
T	0006826	biological_process	iron ion transport
T	0006879	biological_process	intracellular iron ion homeostasis
T	0008198	molecular_function	ferrous iron binding
T	0008199	molecular_function	ferric iron binding
T	0016491	molecular_function	oxidoreductase activity
T	0046872	molecular_function	metal ion binding
U	0004322	molecular_function	ferroxidase activity
U	0005737	cellular_component	cytoplasm
U	0006826	biological_process	iron ion transport
U	0006879	biological_process	intracellular iron ion homeostasis
U	0008198	molecular_function	ferrous iron binding
U	0008199	molecular_function	ferric iron binding
U	0016491	molecular_function	oxidoreductase activity
U	0046872	molecular_function	metal ion binding
V	0004322	molecular_function	ferroxidase activity
V	0005737	cellular_component	cytoplasm
V	0006826	biological_process	iron ion transport
V	0006879	biological_process	intracellular iron ion homeostasis
V	0008198	molecular_function	ferrous iron binding
V	0008199	molecular_function	ferric iron binding
V	0016491	molecular_function	oxidoreductase activity
V	0046872	molecular_function	metal ion binding
W	0004322	molecular_function	ferroxidase activity
W	0005737	cellular_component	cytoplasm
W	0006826	biological_process	iron ion transport
W	0006879	biological_process	intracellular iron ion homeostasis
W	0008198	molecular_function	ferrous iron binding
W	0008199	molecular_function	ferric iron binding
W	0016491	molecular_function	oxidoreductase activity
W	0046872	molecular_function	metal ion binding
X	0004322	molecular_function	ferroxidase activity
X	0005737	cellular_component	cytoplasm
X	0006826	biological_process	iron ion transport
X	0006879	biological_process	intracellular iron ion homeostasis
X	0008198	molecular_function	ferrous iron binding
X	0008199	molecular_function	ferric iron binding
X	0016491	molecular_function	oxidoreductase activity
X	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG A 176

Chain	Residue
A	GLU23
A	GLU58
A	HIS61
A	GLN137

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG A 177

Chain	Residue
A	GLU58
A	GLU103
A	GLN137
A	ASP140

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG B 176

Chain	Residue
B	GLU58
B	HIS61
B	GLN137
B	GLU23

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG B 177

Chain	Residue
B	GLU58
B	GLU103
B	GLN137
B	ASP140

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG C 176

Chain	Residue
C	GLU23
C	GLU58
C	HIS61
C	GLN137

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG C 177

Chain	Residue
C	GLU58
C	GLU103
C	GLN137
C	ASP140

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 176

Chain	Residue
D	GLU23
D	GLU58
D	HIS61
D	GLN137

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG D 177

Chain	Residue
D	GLU58
D	GLU103
D	GLN137
D	ASP140

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG E 176

Chain	Residue
E	GLU23
E	GLU58
E	HIS61
E	GLN137

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG E 177

Chain	Residue
E	GLU58
E	GLU103
E	GLN137
E	ASP140

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG F 176

Chain	Residue
F	GLU23
F	GLU58
F	HIS61
F	GLN137

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG F 177

Chain	Residue
F	GLU58
F	GLU103
F	GLN137
F	ASP140

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG G 176

Chain	Residue
G	GLU23
G	GLU58
G	HIS61
G	GLN137

site_id	BC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG G 177

Chain	Residue
G	GLU58
G	GLU103
G	GLN137
G	ASP140

site_id	BC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG H 176

Chain	Residue
H	GLU23
H	GLU58
H	HIS61
H	GLN137

site_id	BC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG H 177

Chain	Residue
H	GLU58
H	GLU103
H	GLN137
H	ASP140

site_id	BC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG I 176

Chain	Residue
I	GLU23
I	GLU58
I	HIS61
I	GLN137

site_id	BC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG I 177

Chain	Residue
I	GLU58
I	GLU103
I	GLN137
I	ASP140

site_id	CC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG J 176

Chain	Residue
J	GLU23
J	GLU58
J	HIS61
J	GLN137

site_id	CC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG J 177

Chain	Residue
J	GLU58
J	GLU103
J	GLN137
J	ASP140

site_id	CC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG K 176

Chain	Residue
K	GLU23
K	GLU58
K	HIS61
K	GLN137

site_id	CC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG K 177

Chain	Residue
K	GLU58
K	GLU103
K	GLN137
K	ASP140

site_id	CC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG L 176

Chain	Residue
L	GLU23
L	GLU58
L	HIS61
L	GLN137

site_id	CC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG L 177

Chain	Residue
L	GLU58
L	GLU103
L	GLN137
L	ASP140

site_id	CC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG M 176

Chain	Residue
M	GLN137
M	GLU23
M	GLU58
M	HIS61

site_id	CC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG M 177

Chain	Residue
M	GLU58
M	GLU103
M	GLN137
M	ASP140

site_id	CC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG N 176

Chain	Residue
N	GLU23
N	GLU58
N	HIS61
N	GLN137

site_id	DC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG N 177

Chain	Residue
N	GLU58
N	GLU103
N	GLN137
N	ASP140

site_id	DC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG O 176

Chain	Residue
O	GLU23
O	GLU58
O	HIS61
O	GLN137

site_id	DC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG O 177

Chain	Residue
O	GLU58
O	GLU103
O	GLN137
O	ASP140

site_id	DC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG P 176

Chain	Residue
P	GLU23
P	GLU58
P	HIS61
P	GLN137

site_id	DC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG P 177

Chain	Residue
P	GLU58
P	GLU103
P	GLN137
P	ASP140

site_id	DC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG Q 176

Chain	Residue
Q	GLU23
Q	GLU58
Q	HIS61
Q	GLN137

site_id	DC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG Q 177

Chain	Residue
Q	GLU58
Q	GLU103
Q	GLN137
Q	ASP140

site_id	DC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG R 176

Chain	Residue
R	GLU23
R	GLU58
R	HIS61
R	GLN137

site_id	DC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG R 177

Chain	Residue
R	GLU58
R	GLU103
R	GLN137
R	ASP140

site_id	EC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG S 176

Chain	Residue
S	GLU23
S	GLU58
S	HIS61
S	GLN137

site_id	EC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG S 177

Chain	Residue
S	GLU58
S	GLU103
S	GLN137
S	ASP140

site_id	EC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG T 176

Chain	Residue
T	GLU23
T	GLU58
T	HIS61
T	GLN137

site_id	EC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG T 177

Chain	Residue
T	GLU58
T	GLU103
T	GLN137
T	ASP140

site_id	EC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG U 176

Chain	Residue
U	GLU23
U	GLU58
U	HIS61
U	GLN137

site_id	EC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG U 177

Chain	Residue
U	GLU58
U	GLU103
U	GLN137
U	ASP140

site_id	EC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG V 176

Chain	Residue
V	GLU23
V	GLU58
V	HIS61
V	GLN137

site_id	EC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG V 177

Chain	Residue
V	GLU58
V	GLU103
V	GLN137
V	ASP140

site_id	EC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG W 176

Chain	Residue
W	GLU23
W	GLU58
W	HIS61
W	GLN137

site_id	FC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG W 177

Chain	Residue
W	GLU58
W	GLU103
W	GLN137
W	ASP140

site_id	FC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG X 176

Chain	Residue
X	GLU23
X	GLU58
X	HIS61
X	GLN137

site_id	FC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG X 177

Chain	Residue
X	GLU58
X	GLU103
X	GLN137
X	ASP140

Functional Information from PROSITE/UniProt

site_id	PS00204
Number of Residues	21
Details	FERRITIN_2 Ferritin iron-binding regions signature 2. DphLCDFLEseYLeeqvkdIK

Chain	Residue	Details
A	ASP122-LYS142

site_id	PS00540
Number of Residues	19
Details	FERRITIN_1 Ferritin iron-binding regions signature 1. EeREhaEKFMkyQNkRgGR

Chain	Residue	Details
A	GLU57-ARG75

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3576
Details	Domain: {"description":"Ferritin-like diiron","evidences":[{"source":"PROSITE-ProRule","id":"PRU00085","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	144
Details	Binding site: {}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)