Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003756 | molecular_function | protein disulfide isomerase activity |
Functional Information from PROSITE/UniProt
| site_id | PS00194 |
| Number of Residues | 19 |
| Details | THIOREDOXIN_1 Thioredoxin family active site. LVeFYapWCGHCKaLapeY |
| Chain | Residue | Details |
| A | LEU28-TYR46 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Nucleophile |
| Chain | Residue | Details |
| A | CYS36 | |
| A | CYS39 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Contributes to redox potential value |
| Chain | Residue | Details |
| A | GLY37 | |
| A | HIS38 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | SITE: Lowers pKa of C-terminal Cys of first active site |
| Chain | Residue | Details |
| A | ARG103 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | a catalytic site defined by CSA, PubMed 8527452, 8672469, 16142915 |
| Chain | Residue | Details |
| A | CYS36 | |
| A | CYS39 | |
| A | GLY37 | |
| A | HIS38 | |
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 191 |
| Chain | Residue | Details |
| A | CYS36 | nucleofuge, nucleophile, proton acceptor, proton donor |
| A | GLY37 | activator, modifies pKa |
| A | HIS38 | modifies pKa, proton acceptor, proton donor |
| A | CYS39 | |
