1MD6

High resolution crystal structure of murine IL-1F5 reveals unique loop conformation for specificity

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001960	biological_process	negative regulation of cytokine-mediated signaling pathway
A	0002376	biological_process	immune system process
A	0005125	molecular_function	cytokine activity
A	0005149	molecular_function	interleukin-1 receptor binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0005737	cellular_component	cytoplasm
A	0006954	biological_process	inflammatory response
A	0006955	biological_process	immune response
A	0007165	biological_process	signal transduction
A	0019732	biological_process	antifungal humoral response
A	0032689	biological_process	negative regulation of type II interferon production
A	0032700	biological_process	negative regulation of interleukin-17 production
A	0032715	biological_process	negative regulation of interleukin-6 production
A	0045087	biological_process	innate immune response
A	0071222	biological_process	cellular response to lipopolysaccharide

Functional Information from PROSITE/UniProt

site_id	PS00253
Number of Residues	21
Details	INTERLEUKIN_1 Interleukin-1 signature. FeSAayPgwFLCTspeadqpV

Chain	Residue	Details
A	PHE110-VAL130

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