1MD2

CHOLERA TOXIN B-PENTAMER WITH DECAVALENT LIGAND BMSC-0013

Functional Information from GO Data

Chain	GOid	namespace	contents
D	0005515	molecular_function	protein binding
D	0005534	molecular_function	galactose binding
D	0005576	cellular_component	extracellular region
D	0016020	cellular_component	membrane
D	0020002	cellular_component	host cell plasma membrane
D	0033644	cellular_component	host cell membrane
D	0035821	biological_process	modulation of process of another organism
D	0042531	biological_process	positive regulation of tyrosine phosphorylation of STAT protein
D	0042597	cellular_component	periplasmic space
D	0046812	molecular_function	host cell surface binding
D	0090729	molecular_function	toxin activity
D	1902494	cellular_component	catalytic complex
E	0005515	molecular_function	protein binding
E	0005534	molecular_function	galactose binding
E	0005576	cellular_component	extracellular region
E	0016020	cellular_component	membrane
E	0020002	cellular_component	host cell plasma membrane
E	0033644	cellular_component	host cell membrane
E	0035821	biological_process	modulation of process of another organism
E	0042531	biological_process	positive regulation of tyrosine phosphorylation of STAT protein
E	0042597	cellular_component	periplasmic space
E	0046812	molecular_function	host cell surface binding
E	0090729	molecular_function	toxin activity
E	1902494	cellular_component	catalytic complex
F	0005515	molecular_function	protein binding
F	0005534	molecular_function	galactose binding
F	0005576	cellular_component	extracellular region
F	0016020	cellular_component	membrane
F	0020002	cellular_component	host cell plasma membrane
F	0033644	cellular_component	host cell membrane
F	0035821	biological_process	modulation of process of another organism
F	0042531	biological_process	positive regulation of tyrosine phosphorylation of STAT protein
F	0042597	cellular_component	periplasmic space
F	0046812	molecular_function	host cell surface binding
F	0090729	molecular_function	toxin activity
F	1902494	cellular_component	catalytic complex
G	0005515	molecular_function	protein binding
G	0005534	molecular_function	galactose binding
G	0005576	cellular_component	extracellular region
G	0016020	cellular_component	membrane
G	0020002	cellular_component	host cell plasma membrane
G	0033644	cellular_component	host cell membrane
G	0035821	biological_process	modulation of process of another organism
G	0042531	biological_process	positive regulation of tyrosine phosphorylation of STAT protein
G	0042597	cellular_component	periplasmic space
G	0046812	molecular_function	host cell surface binding
G	0090729	molecular_function	toxin activity
G	1902494	cellular_component	catalytic complex
H	0005515	molecular_function	protein binding
H	0005534	molecular_function	galactose binding
H	0005576	cellular_component	extracellular region
H	0016020	cellular_component	membrane
H	0020002	cellular_component	host cell plasma membrane
H	0033644	cellular_component	host cell membrane
H	0035821	biological_process	modulation of process of another organism
H	0042531	biological_process	positive regulation of tyrosine phosphorylation of STAT protein
H	0042597	cellular_component	periplasmic space
H	0046812	molecular_function	host cell surface binding
H	0090729	molecular_function	toxin activity
H	1902494	cellular_component	catalytic complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CYN F 1208

Chain	Residue
F	2331207
F	2331207

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site_id	AC2
Number of Residues	19
Details	BINDING SITE FOR RESIDUE 233 D 2201

Chain	Residue
D	ASN90
D	LYS91
D	SQ2202
D	2332203
D	HOH2244
D	HOH2260
D	HOH2319
D	HOH2345
D	HOH2349
E	HOH1227
H	ILE58
H	ASP59
D	HIS13
D	GLU51
D	GLN56
D	HIS57
D	ILE58
D	GLN61
D	TRP88

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site_id	AC3
Number of Residues	19
Details	BINDING SITE FOR RESIDUE 233 D 2203

Chain	Residue
D	2332201
D	SQ2202
D	HOH2224
D	HOH2321
E	GLN16
H	GLU51
H	SER55
H	GLN56
H	HIS57
H	ILE58
H	GLN61
H	TRP88
H	ASN90
H	LYS91
H	HOH127
H	HOH133
H	HOH134
H	HOH173
H	HOH250

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site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SQ D 2202

Chain	Residue
D	2332201
D	2332203
E	GLN16
E	HIS18

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site_id	AC5
Number of Residues	15
Details	BINDING SITE FOR RESIDUE 233 E 1204

Chain	Residue
E	GLU51
E	GLN56
E	HIS57
E	GLN61
E	TRP88
E	ASN90
E	LYS91
E	SQ1205
E	2331206
E	HOH1245
E	HOH1280
E	HOH1287
E	HOH1311
F	HOH1225
G	SER55

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site_id	AC6
Number of Residues	19
Details	BINDING SITE FOR RESIDUE 233 E 1206

Chain	Residue
E	2331204
E	SQ1205
G	GLU51
G	SER55
G	GLN56
G	HIS57
G	ILE58
G	GLN61
G	TRP88
G	ASN90
G	LYS91
G	HOH115
G	HOH129
G	HOH132
G	HOH139
G	HOH182
G	HOH220
G	HOH239
H	HOH128

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site_id	AC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SQ E 1205

Chain	Residue
E	2331204
E	2331206
E	HOH1253
E	HOH1311
G	GLY54
G	SER55
G	HIS57
G	LYS62

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site_id	AC8
Number of Residues	14
Details	BINDING SITE FOR RESIDUE 233 F 1207

Chain	Residue
F	HOH1332
F	GLU51
F	SER55
F	GLN56
F	HIS57
F	GLN61
F	TRP88
F	ASN90
F	LYS91
F	CYN1208
F	CYN1208
F	HOH1228
F	HOH1237
F	HOH1321

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