1M6E

CRYSTAL STRUCTURE OF SALICYLIC ACID CARBOXYL METHYLTRANSFERASE (SAMT)

Functional Information from GO Data

Chain	GOid	namespace	contents
X	0008168	molecular_function	methyltransferase activity
X	0008757	molecular_function	S-adenosylmethionine-dependent methyltransferase activity
X	0032259	biological_process	methylation
X	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	17
Details	BINDING SITE FOR RESIDUE SAH X 2814

Chain	Residue
X	HIS8
X	ASP98
X	LEU99
X	GLY128
X	SER129
X	PHE130
X	SER146
X	TYR147
X	SER148
X	LYS10
X	TYR18
X	GLN25
X	ILE29
X	GLY59
X	SER61
X	ASN65
X	ASN97

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SAL X 2000

Chain	Residue
X	GLN25
X	TRP151
X	TYR255
X	MET308
X	VAL311

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	BINDING: BINDING => ECO:0000250|UniProtKB:A4GE70

Chain	Residue	Details
X	TYR18
X	LEU96
X	TYR147

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000250|UniProtKB:A4GE69

Chain	Residue	Details
X	ASN21
X	GLY59

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site_id	SWS_FT_FI3
Number of Residues	5
Details	BINDING: BINDING => ECO:0000269|PubMed:12897246, ECO:0007744|PDB:1M6E

Chain	Residue	Details
X	GLN25
X	ASP98
X	SER129
X	TRP151
X	TYR255

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site_id	SWS_FT_FI4
Number of Residues	6
Details	BINDING: BINDING => ECO:0000250|UniProtKB:Q9FLN8

Chain	Residue	Details
X	ASN65
X	SER146
X	ASN162
X	ASP248
X	PHE250
X	ASN251

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