Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0008800 | molecular_function | beta-lactamase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0017001 | biological_process | antibiotic catabolic process |
| A | 0030655 | biological_process | beta-lactam antibiotic catabolic process |
| A | 0046677 | biological_process | response to antibiotic |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PO4 A 501 |
| Chain | Residue |
| A | LYS55 |
| A | LYS215 |
| A | HOH1127 |
| A | HOH1266 |
| A | HOH1396 |
| A | HOH1529 |
| A | HOH1539 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 A 502 |
| Chain | Residue |
| A | HOH1485 |
| A | HOH1524 |
| A | HOH1537 |
| A | ARG161 |
| A | HOH1392 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE PO4 A 503 |
| Chain | Residue |
| A | THR271 |
| A | ASP273 |
| A | GLU274 |
| A | ARG277 |
| A | HOH1189 |
| A | HOH1313 |
| A | HOH1445 |
| A | HOH1511 |
| A | HOH1518 |
| A | HOH1521 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE K A 1000 |
| Chain | Residue |
| A | LEU57 |
| A | GLU58 |
| A | ASN100 |
| A | HOH1088 |
| A | HOH1161 |
| A | HOH1182 |
| A | HOH1183 |
| A | HOH1220 |
| A | HOH1254 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE K A 1001 |
| Chain | Residue |
| A | TYR97 |
| A | LEU113 |
| A | HOH1098 |
| A | HOH1146 |
| A | HOH1148 |
| A | HOH1192 |
| A | HOH1202 |
| A | HOH1203 |
| A | HOH1556 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE K A 1002 |
| Chain | Residue |
| A | GLU240 |
| A | CB4300 |
| A | HOH1019 |
| A | HOH1054 |
| A | HOH1075 |
| A | HOH1085 |
| A | HOH1184 |
| A | HOH1241 |
| A | HOH1554 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE K A 1003 |
| Chain | Residue |
| A | MET211 |
| A | ALA213 |
| A | ASP214 |
| A | ASP233 |
| A | HOH1421 |
| site_id | AC8 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE CB4 A 300 |
| Chain | Residue |
| A | MET69 |
| A | SER70 |
| A | TYR105 |
| A | SER130 |
| A | ASN132 |
| A | GLY236 |
| A | ALA237 |
| A | GLY238 |
| A | GLU240 |
| A | K1002 |
| A | HOH1038 |
| A | HOH1068 |
| A | HOH1076 |
| A | HOH1129 |
| A | HOH1138 |
| A | HOH1141 |
| A | HOH1144 |
| A | HOH1253 |
| A | HOH1270 |
| A | HOH1271 |
| A | HOH1276 |
Functional Information from PROSITE/UniProt
| site_id | PS00146 |
| Number of Residues | 16 |
| Details | BETA_LACTAMASE_A Beta-lactamase class-A active site. FpMMSTfKvllCGAVL |
| Chain | Residue | Details |
| A | PHE66-LEU81 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Acyl-ester intermediate"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1btl |
| Chain | Residue | Details |
| A | GLU166 | |
| A | LYS73 | |
| A | SER130 | |
| A | SER70 |
| site_id | MCSA1 |
| Number of Residues | 6 |
| Details | M-CSA 2 |
| Chain | Residue | Details |
| A | SER70 | electrostatic stabiliser |
| A | LYS73 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | SER130 | activator, electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | GLU166 | activator, electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | LYS234 | electrostatic stabiliser |
| A | ALA237 | electrostatic stabiliser, hydrogen bond donor |
