Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1M3D

Structure of Type IV Collagen NC1 Domains

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005201	molecular_function	extracellular matrix structural constituent
A	0005581	cellular_component	collagen trimer
B	0005201	molecular_function	extracellular matrix structural constituent
B	0005581	cellular_component	collagen trimer
C	0005201	molecular_function	extracellular matrix structural constituent
C	0005576	cellular_component	extracellular region
C	0005581	cellular_component	collagen trimer
C	0005604	cellular_component	basement membrane
D	0005201	molecular_function	extracellular matrix structural constituent
D	0005581	cellular_component	collagen trimer
E	0005201	molecular_function	extracellular matrix structural constituent
E	0005581	cellular_component	collagen trimer
F	0005201	molecular_function	extracellular matrix structural constituent
F	0005576	cellular_component	extracellular region
F	0005581	cellular_component	collagen trimer
F	0005604	cellular_component	basement membrane
G	0005201	molecular_function	extracellular matrix structural constituent
G	0005581	cellular_component	collagen trimer
H	0005201	molecular_function	extracellular matrix structural constituent
H	0005581	cellular_component	collagen trimer
I	0005201	molecular_function	extracellular matrix structural constituent
I	0005576	cellular_component	extracellular region
I	0005581	cellular_component	collagen trimer
I	0005604	cellular_component	basement membrane
J	0005201	molecular_function	extracellular matrix structural constituent
J	0005581	cellular_component	collagen trimer
K	0005201	molecular_function	extracellular matrix structural constituent
K	0005581	cellular_component	collagen trimer
L	0005201	molecular_function	extracellular matrix structural constituent
L	0005576	cellular_component	extracellular region
L	0005581	cellular_component	collagen trimer
L	0005604	cellular_component	basement membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE LU C 2001

Chain	Residue
C	ASP148
C	GLU149
C	HOH3063
F	ASP148
F	HOH3127

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE LU F 2002

Chain	Residue
F	HOH3067
B	HOH4078
C	ASP148
F	ASP148
F	GLU149

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE LU I 2003

Chain	Residue
I	ASP148
I	GLU149
I	HOH3038
L	ASP148
L	HOH3116

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE LU L 2004

Chain	Residue
I	HOH3110
L	ASP148
L	GLU149
L	HOH3046

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR A 3001

Chain	Residue
A	ASN66
B	TYR189
D	ALA186

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR A 3002

Chain	Residue
A	ALA186
D	ASN66
E	TYR189

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE BR E 3003

Chain	Residue
E	ALA74
E	ARG76
E	ASP78
E	GLY178

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE BR A 3004

Chain	Residue
A	ARG179
D	ALA74
D	ARG76
D	ASP78
D	GLY178

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE BR A 3005

Chain	Residue
A	ALA74
A	ARG76
A	ASP78
A	GLY178
D	ARG179

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE BR H 3006

Chain	Residue
H	ALA74
H	ARG76
H	ASP78
H	GLY178

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE BR C 3007

Chain	Residue
C	ALA73
C	ARG75
C	ASP77
C	HOH3064

site_id	BC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE BR J 3008

Chain	Residue
G	ARG179
J	ALA74
J	ARG76
J	ASP78
J	GLY178

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE BR K 3009

Chain	Residue
K	ALA74
K	ARG76
K	ASP78
K	GLY178

site_id	BC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE BR L 3010

Chain	Residue
L	ALA73
L	ARG75
L	ASP77
L	HOH3066

site_id	BC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR H 3011

Chain	Residue
G	ASN66
H	TYR189
J	ALA186

site_id	BC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE BR B 3012

Chain	Residue
B	ALA74
B	ARG76
B	ASP78
B	GLY178

site_id	BC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE BR F 3013

Chain	Residue
B	HOH4010
F	ALA73
F	ARG75
F	ASP77
F	HOH3053

site_id	BC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE BR I 3014

Chain	Residue
I	ALA73
I	ARG75
I	ASP77
I	HOH3052

site_id	CC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR G 3015

Chain	Residue
G	ALA186
J	ASN66
K	TYR189

site_id	CC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE BR G 3016

Chain	Residue
G	ALA74
G	ARG76
G	ASP78
J	ARG179

site_id	CC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR L 3017

Chain	Residue
L	GLY211
L	ILE213
L	ARG214

site_id	CC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE BR C 3018

Chain	Residue
A	TYR189
C	TYR63
C	ASN65
C	TYR71
E	ALA186

site_id	CC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR C 3019

Chain	Residue
C	ALA184
E	ASN66
F	TYR187

site_id	CC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE BR H 3020

Chain	Residue
H	ASN66
I	TYR187
L	TYR183
L	ALA184

site_id	CC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR B 3021

Chain	Residue
C	TYR187
F	ALA184
B	ASN66

site_id	CC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE BR F 3022

Chain	Residue
B	ALA186
D	TYR189
F	TYR63
F	ASN65

site_id	CC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE BR I 3023

Chain	Residue
G	TYR189
I	TYR63
I	ASN65
K	ALA186

site_id	DC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR I 3024

Chain	Residue
I	ALA184
K	ASN66
L	TYR187

site_id	DC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE BR L 3025

Chain	Residue
H	ALA186
J	TYR189
L	TYR63
L	ASN65

site_id	DC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BR B 3026

Chain	Residue
B	ARG55

site_id	DC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE BR K 3027

Chain	Residue
K	ARG55
L	HOH3098

site_id	DC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR B 3028

Chain	Residue
B	PHE168
B	ARG216
B	HOH4074

site_id	DC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR C 3029

Chain	Residue
C	GLY211
C	ILE213
C	ARG214

site_id	DC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR D 3030

Chain	Residue
D	GLY213
D	LEU215
D	ARG216

site_id	DC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR G 3031

Chain	Residue
G	GLY213
G	LEU215
G	ARG216

site_id	DC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR J 3032

Chain	Residue
J	GLY213
J	LEU215
J	ARG216

site_id	EC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE BR K 3033

Chain	Residue
K	GLY213
K	GLU214
K	LEU215
K	ARG216

site_id	EC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE BR B 3034

Chain	Residue
B	GLY213
B	GLU214
B	LEU215
B	ARG216

site_id	EC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE BR H 3035

Chain	Residue
H	GLY213
H	GLU214
H	LEU215
H	ARG216

site_id	EC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE BR E 3036

Chain	Residue
E	GLY213
E	LEU215
E	ARG216

site_id	EC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 4001

Chain	Residue
A	ALA194
A	THR195
A	SER208
A	HIS218
C	LEU62
C	TYR72

site_id	EC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL B 4002

Chain	Residue
A	LEU63
A	PHE73
B	ALA194
B	THR195
B	HIS218

site_id	EC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL D 4003

Chain	Residue
D	THR195
D	HIS218
F	LEU62
F	TYR72

site_id	EC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL E 4004

Chain	Residue
D	LEU63
D	PHE73
E	ALA194
E	THR195
E	SER208
E	HIS218

site_id	EC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL G 4005

Chain	Residue
G	ALA194
G	THR195
G	HIS218
I	LEU62
I	TYR72

site_id	FC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL H 4006

Chain	Residue
G	LEU63
G	PHE73
H	ALA194
H	THR195
H	SER208
H	HIS218

site_id	FC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL J 4007

Chain	Residue
J	ALA194
J	THR195
J	HIS218
J	HOH4099
L	LEU62
L	TYR72

site_id	FC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL K 4008

Chain	Residue
J	LEU63
J	PHE73
K	ALA194
K	THR195
K	HIS218

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	MOD_RES: 3-hydroxyproline => ECO:0000269\|PubMed:24368846

Chain	Residue	Details
A	LYS204
E	LYS204
E	PRO207
E	LEU210
G	LYS204
G	PRO207
G	LEU210
H	LYS204
H	PRO207
H	LEU210
J	LYS204
A	PRO207
J	PRO207
J	LEU210
K	LYS204
K	PRO207
K	LEU210
A	LEU210
B	LYS204
B	PRO207
B	LEU210
D	LYS204
D	PRO207
D	LEU210

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)