1M32
Crystal Structure of 2-aminoethylphosphonate Transaminase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008483 | molecular_function | transaminase activity |
| A | 0019700 | biological_process | organic phosphonate catabolic process |
| A | 0047304 | molecular_function | 2-aminoethylphosphonate-pyruvate transaminase activity |
| B | 0008483 | molecular_function | transaminase activity |
| B | 0019700 | biological_process | organic phosphonate catabolic process |
| B | 0047304 | molecular_function | 2-aminoethylphosphonate-pyruvate transaminase activity |
| C | 0008483 | molecular_function | transaminase activity |
| C | 0019700 | biological_process | organic phosphonate catabolic process |
| C | 0047304 | molecular_function | 2-aminoethylphosphonate-pyruvate transaminase activity |
| D | 0008483 | molecular_function | transaminase activity |
| D | 0019700 | biological_process | organic phosphonate catabolic process |
| D | 0047304 | molecular_function | 2-aminoethylphosphonate-pyruvate transaminase activity |
| E | 0008483 | molecular_function | transaminase activity |
| E | 0019700 | biological_process | organic phosphonate catabolic process |
| E | 0047304 | molecular_function | 2-aminoethylphosphonate-pyruvate transaminase activity |
| F | 0008483 | molecular_function | transaminase activity |
| F | 0019700 | biological_process | organic phosphonate catabolic process |
| F | 0047304 | molecular_function | 2-aminoethylphosphonate-pyruvate transaminase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 B 4602 |
| Chain | Residue |
| B | GLY11 |
| B | TYR91 |
| B | TYR328 |
| B | HOH4949 |
| B | HOH4952 |
| B | HOH4956 |
| B | HOH4964 |
| B | HOH5068 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PO4 C 4604 |
| Chain | Residue |
| C | THR242 |
| C | HOH4944 |
| D | TYR91 |
| D | TYR328 |
| D | HOH4753 |
| D | HOH4840 |
| D | HOH4868 |
| D | HOH4903 |
| C | TRP30 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PO4 E 4605 |
| Chain | Residue |
| E | TYR91 |
| E | TYR328 |
| E | HOH4975 |
| E | HOH4978 |
| E | HOH4979 |
| E | HOH4981 |
| E | HOH5090 |
| F | THR242 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PO4 F 4606 |
| Chain | Residue |
| E | THR242 |
| E | HOH4987 |
| F | TYR91 |
| F | TYR328 |
| F | HOH4986 |
| F | HOH4987 |
| F | HOH5097 |
| F | HOH5101 |
| F | HOH5136 |
| site_id | AC5 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE PLP A 4401 |
| Chain | Residue |
| A | SER64 |
| A | GLY65 |
| A | SER66 |
| A | TYR91 |
| A | VAL138 |
| A | SER140 |
| A | THR142 |
| A | ASP167 |
| A | MSE169 |
| A | HOH4662 |
| A | HOH4669 |
| A | HOH4959 |
| A | HOH5101 |
| B | PHE241 |
| B | THR242 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE POA A 4601 |
| Chain | Residue |
| A | TYR91 |
| A | TYR328 |
| A | ARG339 |
| A | HOH4883 |
| A | HOH4960 |
| A | HOH4961 |
| A | HOH4962 |
| A | HOH4979 |
| A | HOH5101 |
| B | HOH4987 |
| site_id | AC7 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE PLP B 4402 |
| Chain | Residue |
| A | THR242 |
| B | SER64 |
| B | GLY65 |
| B | SER66 |
| B | TYR91 |
| B | VAL138 |
| B | SER140 |
| B | THR142 |
| B | ASP167 |
| B | MSE169 |
| B | SER170 |
| B | LYS193 |
| B | HOH4616 |
| B | HOH4727 |
| B | HOH4949 |
| B | HOH5108 |
| site_id | AC8 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE PLP C 4403 |
| Chain | Residue |
| C | SER64 |
| C | GLY65 |
| C | SER66 |
| C | TYR91 |
| C | VAL138 |
| C | SER140 |
| C | THR142 |
| C | ASP167 |
| C | MSE169 |
| C | LYS193 |
| C | POA4603 |
| C | HOH4618 |
| C | HOH4691 |
| C | HOH4942 |
| C | HOH5085 |
| D | PHE241 |
| D | THR242 |
| site_id | AC9 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE POA C 4603 |
| Chain | Residue |
| C | HOH5062 |
| C | HOH5085 |
| D | THR242 |
| C | TYR91 |
| C | TYR328 |
| C | ARG339 |
| C | PLP4403 |
| C | HOH4816 |
| C | HOH4942 |
| C | HOH4972 |
| site_id | BC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE PLP D 4404 |
| Chain | Residue |
| C | PHE241 |
| C | THR242 |
| D | SER64 |
| D | GLY65 |
| D | SER66 |
| D | TYR91 |
| D | VAL138 |
| D | SER140 |
| D | THR142 |
| D | ASP167 |
| D | MSE169 |
| D | HOH4425 |
| D | HOH4498 |
| D | HOH4753 |
| D | HOH4903 |
| site_id | BC2 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE PLP E 4405 |
| Chain | Residue |
| E | SER64 |
| E | GLY65 |
| E | SER66 |
| E | TYR91 |
| E | VAL138 |
| E | SER140 |
| E | THR142 |
| E | ASP167 |
| E | MSE169 |
| E | SER170 |
| E | HOH4629 |
| E | HOH4689 |
| E | HOH4975 |
| E | HOH5123 |
| F | PHE241 |
| F | THR242 |
| site_id | BC3 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE PLP F 4406 |
| Chain | Residue |
| E | PHE241 |
| E | THR242 |
| F | SER64 |
| F | GLY65 |
| F | SER66 |
| F | TYR91 |
| F | VAL138 |
| F | SER140 |
| F | THR142 |
| F | ASP167 |
| F | MSE169 |
| F | LYS193 |
| F | HOH4617 |
| F | HOH4666 |
| F | HOH4986 |
| F | HOH5136 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 30 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | SER64 | |
| B | THR242 | |
| C | SER64 | |
| C | TYR91 | |
| C | THR142 | |
| C | ASP167 | |
| C | THR242 | |
| D | SER64 | |
| D | TYR91 | |
| D | THR142 | |
| D | ASP167 | |
| A | TYR91 | |
| D | THR242 | |
| E | SER64 | |
| E | TYR91 | |
| E | THR142 | |
| E | ASP167 | |
| E | THR242 | |
| F | SER64 | |
| F | TYR91 | |
| F | THR142 | |
| F | ASP167 | |
| A | THR142 | |
| F | THR242 | |
| A | ASP167 | |
| A | THR242 | |
| B | SER64 | |
| B | TYR91 | |
| B | THR142 | |
| B | ASP167 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | MOD_RES: N6-(pyridoxal phosphate)lysine => ECO:0000255 |
| Chain | Residue | Details |
| A | LYS193 | |
| B | LYS193 | |
| C | LYS193 | |
| D | LYS193 | |
| E | LYS193 | |
| F | LYS193 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1b8g |
| Chain | Residue | Details |
| F | TYR91 | |
| F | ASP167 |
| site_id | CSA10 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1b8g |
| Chain | Residue | Details |
| D | LYS193 | |
| D | TYR91 | |
| D | ASP167 |
| site_id | CSA11 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1b8g |
| Chain | Residue | Details |
| E | LYS193 | |
| E | TYR91 | |
| E | ASP167 |
| site_id | CSA12 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1b8g |
| Chain | Residue | Details |
| F | LYS193 | |
| F | TYR91 | |
| F | ASP167 |
| site_id | CSA13 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1b8g |
| Chain | Residue | Details |
| A | ASP33 |
| site_id | CSA14 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1b8g |
| Chain | Residue | Details |
| B | ASP33 |
| site_id | CSA15 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1b8g |
| Chain | Residue | Details |
| C | ASP33 |
| site_id | CSA16 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1b8g |
| Chain | Residue | Details |
| D | ASP33 |
| site_id | CSA17 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1b8g |
| Chain | Residue | Details |
| E | ASP33 |
| site_id | CSA18 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1b8g |
| Chain | Residue | Details |
| F | ASP33 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1b8g |
| Chain | Residue | Details |
| A | TYR91 | |
| A | ASP167 |
| site_id | CSA3 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1b8g |
| Chain | Residue | Details |
| B | TYR91 | |
| B | ASP167 |
| site_id | CSA4 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1b8g |
| Chain | Residue | Details |
| C | TYR91 | |
| C | ASP167 |
| site_id | CSA5 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1b8g |
| Chain | Residue | Details |
| D | TYR91 | |
| D | ASP167 |
| site_id | CSA6 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1b8g |
| Chain | Residue | Details |
| E | TYR91 | |
| E | ASP167 |
| site_id | CSA7 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1b8g |
| Chain | Residue | Details |
| A | LYS193 | |
| A | TYR91 | |
| A | ASP167 |
| site_id | CSA8 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1b8g |
| Chain | Residue | Details |
| B | LYS193 | |
| B | TYR91 | |
| B | ASP167 |
| site_id | CSA9 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1b8g |
| Chain | Residue | Details |
| C | LYS193 | |
| C | TYR91 | |
| C | ASP167 |
