1M32
Crystal Structure of 2-aminoethylphosphonate Transaminase
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0008483 | molecular_function | transaminase activity |
A | 0019700 | biological_process | organic phosphonate catabolic process |
A | 0047304 | molecular_function | 2-aminoethylphosphonate-pyruvate transaminase activity |
B | 0008483 | molecular_function | transaminase activity |
B | 0019700 | biological_process | organic phosphonate catabolic process |
B | 0047304 | molecular_function | 2-aminoethylphosphonate-pyruvate transaminase activity |
C | 0008483 | molecular_function | transaminase activity |
C | 0019700 | biological_process | organic phosphonate catabolic process |
C | 0047304 | molecular_function | 2-aminoethylphosphonate-pyruvate transaminase activity |
D | 0008483 | molecular_function | transaminase activity |
D | 0019700 | biological_process | organic phosphonate catabolic process |
D | 0047304 | molecular_function | 2-aminoethylphosphonate-pyruvate transaminase activity |
E | 0008483 | molecular_function | transaminase activity |
E | 0019700 | biological_process | organic phosphonate catabolic process |
E | 0047304 | molecular_function | 2-aminoethylphosphonate-pyruvate transaminase activity |
F | 0008483 | molecular_function | transaminase activity |
F | 0019700 | biological_process | organic phosphonate catabolic process |
F | 0047304 | molecular_function | 2-aminoethylphosphonate-pyruvate transaminase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE PO4 B 4602 |
Chain | Residue |
B | GLY11 |
B | TYR91 |
B | TYR328 |
B | HOH4949 |
B | HOH4952 |
B | HOH4956 |
B | HOH4964 |
B | HOH5068 |
site_id | AC2 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE PO4 C 4604 |
Chain | Residue |
C | THR242 |
C | HOH4944 |
D | TYR91 |
D | TYR328 |
D | HOH4753 |
D | HOH4840 |
D | HOH4868 |
D | HOH4903 |
C | TRP30 |
site_id | AC3 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE PO4 E 4605 |
Chain | Residue |
E | TYR91 |
E | TYR328 |
E | HOH4975 |
E | HOH4978 |
E | HOH4979 |
E | HOH4981 |
E | HOH5090 |
F | THR242 |
site_id | AC4 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE PO4 F 4606 |
Chain | Residue |
E | THR242 |
E | HOH4987 |
F | TYR91 |
F | TYR328 |
F | HOH4986 |
F | HOH4987 |
F | HOH5097 |
F | HOH5101 |
F | HOH5136 |
site_id | AC5 |
Number of Residues | 15 |
Details | BINDING SITE FOR RESIDUE PLP A 4401 |
Chain | Residue |
A | SER64 |
A | GLY65 |
A | SER66 |
A | TYR91 |
A | VAL138 |
A | SER140 |
A | THR142 |
A | ASP167 |
A | MSE169 |
A | HOH4662 |
A | HOH4669 |
A | HOH4959 |
A | HOH5101 |
B | PHE241 |
B | THR242 |
site_id | AC6 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE POA A 4601 |
Chain | Residue |
A | TYR91 |
A | TYR328 |
A | ARG339 |
A | HOH4883 |
A | HOH4960 |
A | HOH4961 |
A | HOH4962 |
A | HOH4979 |
A | HOH5101 |
B | HOH4987 |
site_id | AC7 |
Number of Residues | 16 |
Details | BINDING SITE FOR RESIDUE PLP B 4402 |
Chain | Residue |
A | THR242 |
B | SER64 |
B | GLY65 |
B | SER66 |
B | TYR91 |
B | VAL138 |
B | SER140 |
B | THR142 |
B | ASP167 |
B | MSE169 |
B | SER170 |
B | LYS193 |
B | HOH4616 |
B | HOH4727 |
B | HOH4949 |
B | HOH5108 |
site_id | AC8 |
Number of Residues | 17 |
Details | BINDING SITE FOR RESIDUE PLP C 4403 |
Chain | Residue |
C | SER64 |
C | GLY65 |
C | SER66 |
C | TYR91 |
C | VAL138 |
C | SER140 |
C | THR142 |
C | ASP167 |
C | MSE169 |
C | LYS193 |
C | POA4603 |
C | HOH4618 |
C | HOH4691 |
C | HOH4942 |
C | HOH5085 |
D | PHE241 |
D | THR242 |
site_id | AC9 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE POA C 4603 |
Chain | Residue |
C | HOH5062 |
C | HOH5085 |
D | THR242 |
C | TYR91 |
C | TYR328 |
C | ARG339 |
C | PLP4403 |
C | HOH4816 |
C | HOH4942 |
C | HOH4972 |
site_id | BC1 |
Number of Residues | 15 |
Details | BINDING SITE FOR RESIDUE PLP D 4404 |
Chain | Residue |
C | PHE241 |
C | THR242 |
D | SER64 |
D | GLY65 |
D | SER66 |
D | TYR91 |
D | VAL138 |
D | SER140 |
D | THR142 |
D | ASP167 |
D | MSE169 |
D | HOH4425 |
D | HOH4498 |
D | HOH4753 |
D | HOH4903 |
site_id | BC2 |
Number of Residues | 16 |
Details | BINDING SITE FOR RESIDUE PLP E 4405 |
Chain | Residue |
E | SER64 |
E | GLY65 |
E | SER66 |
E | TYR91 |
E | VAL138 |
E | SER140 |
E | THR142 |
E | ASP167 |
E | MSE169 |
E | SER170 |
E | HOH4629 |
E | HOH4689 |
E | HOH4975 |
E | HOH5123 |
F | PHE241 |
F | THR242 |
site_id | BC3 |
Number of Residues | 16 |
Details | BINDING SITE FOR RESIDUE PLP F 4406 |
Chain | Residue |
E | PHE241 |
E | THR242 |
F | SER64 |
F | GLY65 |
F | SER66 |
F | TYR91 |
F | VAL138 |
F | SER140 |
F | THR142 |
F | ASP167 |
F | MSE169 |
F | LYS193 |
F | HOH4617 |
F | HOH4666 |
F | HOH4986 |
F | HOH5136 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 30 |
Details | BINDING: |
Chain | Residue | Details |
A | SER64 | |
B | THR242 | |
C | SER64 | |
C | TYR91 | |
C | THR142 | |
C | ASP167 | |
C | THR242 | |
D | SER64 | |
D | TYR91 | |
D | THR142 | |
D | ASP167 | |
A | TYR91 | |
D | THR242 | |
E | SER64 | |
E | TYR91 | |
E | THR142 | |
E | ASP167 | |
E | THR242 | |
F | SER64 | |
F | TYR91 | |
F | THR142 | |
F | ASP167 | |
A | THR142 | |
F | THR242 | |
A | ASP167 | |
A | THR242 | |
B | SER64 | |
B | TYR91 | |
B | THR142 | |
B | ASP167 |
site_id | SWS_FT_FI2 |
Number of Residues | 6 |
Details | MOD_RES: N6-(pyridoxal phosphate)lysine => ECO:0000255 |
Chain | Residue | Details |
A | LYS193 | |
B | LYS193 | |
C | LYS193 | |
D | LYS193 | |
E | LYS193 | |
F | LYS193 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1b8g |
Chain | Residue | Details |
F | TYR91 | |
F | ASP167 |
site_id | CSA10 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1b8g |
Chain | Residue | Details |
D | LYS193 | |
D | TYR91 | |
D | ASP167 |
site_id | CSA11 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1b8g |
Chain | Residue | Details |
E | LYS193 | |
E | TYR91 | |
E | ASP167 |
site_id | CSA12 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1b8g |
Chain | Residue | Details |
F | LYS193 | |
F | TYR91 | |
F | ASP167 |
site_id | CSA13 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1b8g |
Chain | Residue | Details |
A | ASP33 |
site_id | CSA14 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1b8g |
Chain | Residue | Details |
B | ASP33 |
site_id | CSA15 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1b8g |
Chain | Residue | Details |
C | ASP33 |
site_id | CSA16 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1b8g |
Chain | Residue | Details |
D | ASP33 |
site_id | CSA17 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1b8g |
Chain | Residue | Details |
E | ASP33 |
site_id | CSA18 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1b8g |
Chain | Residue | Details |
F | ASP33 |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1b8g |
Chain | Residue | Details |
A | TYR91 | |
A | ASP167 |
site_id | CSA3 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1b8g |
Chain | Residue | Details |
B | TYR91 | |
B | ASP167 |
site_id | CSA4 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1b8g |
Chain | Residue | Details |
C | TYR91 | |
C | ASP167 |
site_id | CSA5 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1b8g |
Chain | Residue | Details |
D | TYR91 | |
D | ASP167 |
site_id | CSA6 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1b8g |
Chain | Residue | Details |
E | TYR91 | |
E | ASP167 |
site_id | CSA7 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1b8g |
Chain | Residue | Details |
A | LYS193 | |
A | TYR91 | |
A | ASP167 |
site_id | CSA8 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1b8g |
Chain | Residue | Details |
B | LYS193 | |
B | TYR91 | |
B | ASP167 |
site_id | CSA9 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1b8g |
Chain | Residue | Details |
C | LYS193 | |
C | TYR91 | |
C | ASP167 |