1M1N
Nitrogenase MoFe protein from Azotobacter vinelandii
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0009399 | biological_process | nitrogen fixation |
| A | 0016163 | molecular_function | nitrogenase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016612 | cellular_component | molybdenum-iron nitrogenase complex |
| A | 0051536 | molecular_function | iron-sulfur cluster binding |
| B | 0009399 | biological_process | nitrogen fixation |
| B | 0016163 | molecular_function | nitrogenase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016612 | cellular_component | molybdenum-iron nitrogenase complex |
| C | 0009399 | biological_process | nitrogen fixation |
| C | 0016163 | molecular_function | nitrogenase activity |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016612 | cellular_component | molybdenum-iron nitrogenase complex |
| C | 0051536 | molecular_function | iron-sulfur cluster binding |
| D | 0009399 | biological_process | nitrogen fixation |
| D | 0016163 | molecular_function | nitrogenase activity |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016612 | cellular_component | molybdenum-iron nitrogenase complex |
| E | 0009399 | biological_process | nitrogen fixation |
| E | 0016163 | molecular_function | nitrogenase activity |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0016612 | cellular_component | molybdenum-iron nitrogenase complex |
| E | 0051536 | molecular_function | iron-sulfur cluster binding |
| F | 0009399 | biological_process | nitrogen fixation |
| F | 0016163 | molecular_function | nitrogenase activity |
| F | 0016491 | molecular_function | oxidoreductase activity |
| F | 0016612 | cellular_component | molybdenum-iron nitrogenase complex |
| G | 0009399 | biological_process | nitrogen fixation |
| G | 0016163 | molecular_function | nitrogenase activity |
| G | 0016491 | molecular_function | oxidoreductase activity |
| G | 0016612 | cellular_component | molybdenum-iron nitrogenase complex |
| G | 0051536 | molecular_function | iron-sulfur cluster binding |
| H | 0009399 | biological_process | nitrogen fixation |
| H | 0016163 | molecular_function | nitrogenase activity |
| H | 0016491 | molecular_function | oxidoreductase activity |
| H | 0016612 | cellular_component | molybdenum-iron nitrogenase complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA D 6492 |
| Chain | Residue |
| B | ARG108 |
| B | GLU109 |
| D | ASP353 |
| D | ASP357 |
| D | HOH7499 |
| D | HOH7568 |
| D | HOH8199 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA B 7492 |
| Chain | Residue |
| B | HOH7493 |
| B | HOH7584 |
| B | HOH8212 |
| D | ARG108 |
| D | GLU109 |
| B | ASP353 |
| B | ASP357 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA H 8492 |
| Chain | Residue |
| F | ARG108 |
| F | GLU109 |
| H | ASP353 |
| H | ASP357 |
| H | HOH2542 |
| H | HOH2778 |
| H | HOH5005 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA F 9492 |
| Chain | Residue |
| F | ASP353 |
| F | ASP357 |
| F | HOH2543 |
| F | HOH5006 |
| H | ARG108 |
| H | GLU109 |
| H | HOH2870 |
| site_id | AC5 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE HCA A 6494 |
| Chain | Residue |
| A | ALA65 |
| A | GLN191 |
| A | GLY424 |
| A | ILE425 |
| A | HIS442 |
| A | CFN6496 |
| A | HOH6501 |
| A | HOH6505 |
| A | HOH6512 |
| A | HOH6527 |
| A | HOH6551 |
| A | HOH6555 |
| A | HOH6640 |
| A | HOH6718 |
| B | HOH7500 |
| B | HOH7614 |
| site_id | AC6 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE CLF B 6498 |
| Chain | Residue |
| A | CYS62 |
| A | TYR64 |
| A | PRO85 |
| A | GLY87 |
| A | CYS88 |
| A | TYR91 |
| A | CYS154 |
| A | GLY185 |
| B | CYS70 |
| B | SER92 |
| B | CYS95 |
| B | TYR98 |
| B | CYS153 |
| B | SER188 |
| site_id | AC7 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE CFN A 6496 |
| Chain | Residue |
| A | VAL70 |
| A | ARG96 |
| A | HIS195 |
| A | TYR229 |
| A | CYS275 |
| A | GLY356 |
| A | GLY357 |
| A | LEU358 |
| A | ARG359 |
| A | PHE381 |
| A | HIS442 |
| A | HCA6494 |
| site_id | AC8 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE HCA C 7494 |
| Chain | Residue |
| C | ALA65 |
| C | GLN191 |
| C | GLY424 |
| C | ILE425 |
| C | HIS442 |
| C | CFN7496 |
| C | HOH7514 |
| C | HOH7516 |
| C | HOH7527 |
| C | HOH7538 |
| C | HOH7561 |
| C | HOH7581 |
| C | HOH7611 |
| C | HOH7728 |
| D | HOH7511 |
| D | HOH7547 |
| site_id | AC9 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE CLF D 7498 |
| Chain | Residue |
| D | SER188 |
| C | CYS62 |
| C | TYR64 |
| C | PRO85 |
| C | GLY87 |
| C | CYS88 |
| C | TYR91 |
| C | CYS154 |
| C | GLY185 |
| D | CYS70 |
| D | SER92 |
| D | CYS95 |
| D | TYR98 |
| D | CYS153 |
| site_id | BC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE CFN C 7496 |
| Chain | Residue |
| C | VAL70 |
| C | ARG96 |
| C | HIS195 |
| C | TYR229 |
| C | CYS275 |
| C | GLY356 |
| C | GLY357 |
| C | ARG359 |
| C | PHE381 |
| C | HIS442 |
| C | HCA7494 |
| site_id | BC2 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE HCA E 8494 |
| Chain | Residue |
| E | ALA65 |
| E | GLN191 |
| E | GLY424 |
| E | ILE425 |
| E | HIS442 |
| E | HOH2561 |
| E | HOH2569 |
| E | HOH2593 |
| E | HOH2691 |
| E | HOH2796 |
| E | HOH2810 |
| E | HOH3220 |
| E | HOH3547 |
| E | CFN8496 |
| F | HOH2571 |
| F | HOH2970 |
| site_id | BC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE CLF F 8498 |
| Chain | Residue |
| E | CYS62 |
| E | TYR64 |
| E | PRO85 |
| E | GLY87 |
| E | CYS88 |
| E | TYR91 |
| E | CYS154 |
| E | GLY185 |
| F | CYS70 |
| F | SER92 |
| F | CYS95 |
| F | TYR98 |
| F | CYS153 |
| F | SER188 |
| site_id | BC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE CFN E 8496 |
| Chain | Residue |
| E | VAL70 |
| E | ARG96 |
| E | HIS195 |
| E | TYR229 |
| E | CYS275 |
| E | GLY356 |
| E | GLY357 |
| E | ARG359 |
| E | PHE381 |
| E | HIS442 |
| E | HCA8494 |
| site_id | BC5 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE HCA G 9494 |
| Chain | Residue |
| G | ALA65 |
| G | GLN191 |
| G | GLY424 |
| G | ILE425 |
| G | HIS442 |
| G | HOH2623 |
| G | HOH2628 |
| G | HOH2681 |
| G | HOH2736 |
| G | HOH2817 |
| G | HOH2920 |
| G | HOH3072 |
| G | HOH3591 |
| G | CFN9496 |
| H | HOH2586 |
| H | HOH2706 |
| site_id | BC6 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE CLF H 9498 |
| Chain | Residue |
| G | CYS62 |
| G | TYR64 |
| G | PRO85 |
| G | GLY87 |
| G | CYS88 |
| G | TYR91 |
| G | CYS154 |
| G | GLY185 |
| H | CYS70 |
| H | SER92 |
| H | CYS95 |
| H | TYR98 |
| H | CYS153 |
| H | SER188 |
| site_id | BC7 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE CFN G 9496 |
| Chain | Residue |
| G | VAL70 |
| G | ARG96 |
| G | HIS195 |
| G | TYR229 |
| G | CYS275 |
| G | GLY356 |
| G | GLY357 |
| G | LEU358 |
| G | ARG359 |
| G | PHE381 |
| G | HIS442 |
| G | HCA9494 |
Functional Information from PROSITE/UniProt
| site_id | PS00090 |
| Number of Residues | 15 |
| Details | NITROGENASE_1_2 Nitrogenases component 1 alpha and beta subunits signature 2. SECpigliGDDIeSV |
| Chain | Residue | Details |
| A | SER152-VAL166 | |
| B | THR151-PHE165 |
| site_id | PS00699 |
| Number of Residues | 8 |
| Details | NITROGENASE_1_1 Nitrogenases component 1 alpha and beta subunits signature 1. ISHGPVGC |
| Chain | Residue | Details |
| A | ILE81-CYS88 | |
| B | TYR88-CYS95 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 36 |
| Details | Binding site: {} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 2 |
| Details | M-CSA 212 |
| Chain | Residue | Details |
| B | CYS153 | metal ligand |
| B | VAL157 | polar interaction, single electron acceptor, single electron donor, single electron relay |
| A | ARG96 | activator, hydrogen bond donor |
| A | HIS195 | activator, polar interaction |
| site_id | MCSA2 |
| Number of Residues | 2 |
| Details | M-CSA 212 |
| Chain | Residue | Details |
| D | CYS153 | metal ligand |
| D | VAL157 | polar interaction, single electron acceptor, single electron donor, single electron relay |
| C | ARG96 | activator, hydrogen bond donor |
| C | HIS195 | activator, polar interaction |
| site_id | MCSA3 |
| Number of Residues | 2 |
| Details | M-CSA 212 |
| Chain | Residue | Details |
| F | CYS153 | metal ligand |
| F | VAL157 | polar interaction, single electron acceptor, single electron donor, single electron relay |
| E | ARG96 | activator, hydrogen bond donor |
| E | HIS195 | activator, polar interaction |
| site_id | MCSA4 |
| Number of Residues | 2 |
| Details | M-CSA 212 |
| Chain | Residue | Details |
| H | CYS153 | metal ligand |
| H | VAL157 | polar interaction, single electron acceptor, single electron donor, single electron relay |
| G | ARG96 | activator, hydrogen bond donor |
| G | HIS195 | activator, polar interaction |
