Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004363 | molecular_function | glutathione synthase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006750 | biological_process | glutathione biosynthetic process |
| A | 0016874 | molecular_function | ligase activity |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0043295 | molecular_function | glutathione binding |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0004363 | molecular_function | glutathione synthase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006750 | biological_process | glutathione biosynthetic process |
| B | 0016874 | molecular_function | ligase activity |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0043295 | molecular_function | glutathione binding |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 502 |
| Chain | Residue |
| A | GLU146 |
| A | ANP504 |
| A | HOH2517 |
| A | HOH2585 |
| A | HOH2603 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 1502 |
| Chain | Residue |
| B | HOH2674 |
| B | GLU1146 |
| B | ANP1504 |
| B | HOH2559 |
| B | HOH2673 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 503 |
| Chain | Residue |
| A | GLU146 |
| A | GLU386 |
| A | ANP504 |
| A | HOH2001 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG B 1503 |
| Chain | Residue |
| B | GLU1146 |
| B | GLU1386 |
| B | ANP1504 |
| B | HOH2732 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 506 |
| Chain | Residue |
| A | LYS136 |
| A | LYS137 |
| A | ARG273 |
| A | HOH2705 |
| A | HOH2707 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 507 |
| Chain | Residue |
| A | ARG163 |
| A | HOH2388 |
| A | HOH2747 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 508 |
| Chain | Residue |
| A | LYS113 |
| A | SER114 |
| B | ARG1366 |
| B | ARG1370 |
| B | HOH2579 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 509 |
| Chain | Residue |
| B | LYS1136 |
| B | LYS1137 |
| B | ARG1273 |
| B | HOH2699 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 510 |
| Chain | Residue |
| B | ARG1163 |
| B | HOH2478 |
| B | HOH2528 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 511 |
| Chain | Residue |
| A | GLY389 |
| A | ASN391 |
| A | TYR393 |
| A | ANP504 |
| A | HOH2581 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 512 |
| Chain | Residue |
| B | GLY1389 |
| B | ASN1390 |
| B | ASN1391 |
| B | TYR1393 |
| B | ANP1504 |
| B | HOH2374 |
| site_id | BC3 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE ANP A 504 |
| Chain | Residue |
| A | VAL145 |
| A | GLU146 |
| A | LYS324 |
| A | LYS382 |
| A | GLU386 |
| A | GLY387 |
| A | ASN391 |
| A | TYR393 |
| A | MET415 |
| A | GLU416 |
| A | LEU417 |
| A | ILE418 |
| A | GLU442 |
| A | LYS469 |
| A | 3GC501 |
| A | MG502 |
| A | MG503 |
| A | SO4511 |
| A | HOH2013 |
| A | HOH2107 |
| A | HOH2233 |
| A | HOH2353 |
| A | HOH2517 |
| A | HOH2585 |
| A | HOH2603 |
| A | HOH2724 |
| site_id | BC4 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE ANP B 1504 |
| Chain | Residue |
| B | HOH2674 |
| B | SO4512 |
| B | VAL1145 |
| B | GLU1146 |
| B | LYS1324 |
| B | VAL1380 |
| B | LYS1382 |
| B | GLU1386 |
| B | ASN1391 |
| B | TYR1393 |
| B | MET1415 |
| B | GLU1416 |
| B | LEU1417 |
| B | ILE1418 |
| B | GLU1442 |
| B | LYS1469 |
| B | 3GC1501 |
| B | MG1502 |
| B | MG1503 |
| B | HOH2189 |
| B | HOH2372 |
| B | HOH2376 |
| B | HOH2554 |
| B | HOH2559 |
| B | HOH2673 |
| site_id | BC5 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE 3GC A 501 |
| Chain | Residue |
| A | ARG128 |
| A | ASN148 |
| A | VAL150 |
| A | SER151 |
| A | VAL152 |
| A | SER153 |
| A | GLU228 |
| A | ASN230 |
| A | GLN234 |
| A | ARG285 |
| A | TYR288 |
| A | ARG467 |
| A | ANP504 |
| A | HOH2298 |
| A | HOH2517 |
| A | HOH2724 |
| site_id | BC6 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE 3GC B 1501 |
| Chain | Residue |
| B | ARG1128 |
| B | VAL1150 |
| B | SER1151 |
| B | VAL1152 |
| B | SER1153 |
| B | GLU1228 |
| B | ASN1230 |
| B | GLN1234 |
| B | ARG1285 |
| B | TYR1288 |
| B | ARG1467 |
| B | ANP1504 |
| B | HOH2286 |
| B | HOH2674 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12467574","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 43 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 2hgs |
| Chain | Residue | Details |
| A | ARG467 | |
| A | GLY387 | |
| A | ARG128 | |
| A | SER153 | |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 2hgs |
| Chain | Residue | Details |
| B | GLY1389 | |
| B | ARG1467 | |
| B | ARG1128 | |
| B | SER1153 | |
