1LXF

Structure of the Regulatory N-domain of Human Cardiac Troponin C in Complex with Human Cardiac Troponin-I(147-163) and Bepridil

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0005509	molecular_function	calcium ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA C 93

Chain	Residue
C	VAL64
C	ASP65
C	ASP67
C	SER69
C	THR71
C	GLU76

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site_id	AC2
Number of Residues	13
Details	BINDING SITE FOR RESIDUE BEP C 92

Chain	Residue
C	LEU48
C	MET60
C	ILE61
C	VAL72
C	PHE77
C	MET80
C	MET81
C	CYS84
I	ILE148
I	MET153
C	PHE27
C	LEU41
C	MET45

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Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DEDGSGTVDfdEF

Chain	Residue	Details
C	ASP65-PHE77

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: Phosphoserine; by PAK3 => ECO:0000269|PubMed:12242269

Chain	Residue	Details
I	SER149
C	ASP67
C	SER69
C	THR71
C	GLU76

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N-acetylmethionine => ECO:0000269|PubMed:3951483

Chain	Residue	Details
C	MET1

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