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1LV9

CXCR3 Binding Chemokine IP-10/CXCL10

Functional Information from GO Data
ChainGOidnamespacecontents
A0002690biological_processpositive regulation of leukocyte chemotaxis
A0005102molecular_functionsignaling receptor binding
A0005125molecular_functioncytokine activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0006935biological_processchemotaxis
A0006952biological_processdefense response
A0006954biological_processinflammatory response
A0006955biological_processimmune response
A0007165biological_processsignal transduction
A0007166biological_processcell surface receptor signaling pathway
A0007186biological_processG protein-coupled receptor signaling pathway
A0007189biological_processadenylate cyclase-activating G protein-coupled receptor signaling pathway
A0007267biological_processcell-cell signaling
A0007517biological_processmuscle organ development
A0008009molecular_functionchemokine activity
A0008015biological_processblood circulation
A0008201molecular_functionheparin binding
A0008284biological_processpositive regulation of cell population proliferation
A0008603molecular_functioncAMP-dependent protein kinase regulator activity
A0009897cellular_componentexternal side of plasma membrane
A0010332biological_processresponse to gamma radiation
A0010818biological_processT cell chemotaxis
A0010819biological_processregulation of T cell chemotaxis
A0010996biological_processresponse to auditory stimulus
A0016525biological_processnegative regulation of angiogenesis
A0030335biological_processpositive regulation of cell migration
A0030593biological_processneutrophil chemotaxis
A0032496biological_processresponse to lipopolysaccharide
A0033280biological_processresponse to vitamin D
A0034605biological_processcellular response to heat
A0042056molecular_functionchemoattractant activity
A0042118biological_processendothelial cell activation
A0042127biological_processregulation of cell population proliferation
A0042981biological_processregulation of apoptotic process
A0045236molecular_functionCXCR chemokine receptor binding
A0045944biological_processpositive regulation of transcription by RNA polymerase II
A0048248molecular_functionCXCR3 chemokine receptor binding
A0050918biological_processpositive chemotaxis
A0051281biological_processpositive regulation of release of sequestered calcium ion into cytosol
A0070098biological_processchemokine-mediated signaling pathway
A0071222biological_processcellular response to lipopolysaccharide
A0090026biological_processpositive regulation of monocyte chemotaxis
A0097398biological_processcellular response to interleukin-17
A0098586biological_processcellular response to virus
A0140374biological_processantiviral innate immune response
A1901509biological_processregulation of endothelial tube morphogenesis
A2000406biological_processpositive regulation of T cell migration
Functional Information from PROSITE/UniProt
site_idPS00471
Number of Residues47
DetailsSMALL_CYTOKINES_CXC Small cytokines (intercrine/chemokine) C-x-C subfamily signature. CtCIsisnqpVnpRsLekLeiipaSqfCprvEIIatmkkkgekrCLN
ChainResidueDetails
ACYS9-ASN55

246704

PDB entries from 2025-12-24

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