1LQK
High Resolution Structure of Fosfomycin Resistance Protein A (FosA)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004364 | molecular_function | glutathione transferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016740 | molecular_function | transferase activity |
| A | 0046677 | biological_process | response to antibiotic |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004364 | molecular_function | glutathione transferase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0016740 | molecular_function | transferase activity |
| B | 0046677 | biological_process | response to antibiotic |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE PO4 B 401 |
| Chain | Residue |
| A | HIS7 |
| B | HOH840 |
| B | HOH978 |
| B | HOH979 |
| B | HOH980 |
| B | HOH981 |
| B | HIS64 |
| B | LYS90 |
| B | SER94 |
| B | TYR100 |
| B | GLU110 |
| B | ARG119 |
| B | K601 |
| B | MN801 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PO4 A 501 |
| Chain | Residue |
| A | HIS64 |
| A | LYS90 |
| A | SER94 |
| A | TYR100 |
| A | GLU110 |
| A | ARG119 |
| A | K701 |
| A | MN901 |
| A | HOH1057 |
| A | HOH1058 |
| B | HIS7 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE K B 601 |
| Chain | Residue |
| B | ASN92 |
| B | SER94 |
| B | GLU95 |
| B | GLY96 |
| B | SER98 |
| B | TYR100 |
| B | ARG119 |
| B | PO4401 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE K A 701 |
| Chain | Residue |
| A | ASN92 |
| A | SER94 |
| A | GLU95 |
| A | GLY96 |
| A | SER98 |
| A | TYR100 |
| A | HIS112 |
| A | ARG119 |
| A | PO4501 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN B 801 |
| Chain | Residue |
| A | HIS7 |
| B | HIS64 |
| B | GLU110 |
| B | PO4401 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN A 901 |
| Chain | Residue |
| A | HIS64 |
| A | GLU110 |
| A | PO4501 |
| B | HIS7 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 220 |
| Details | Domain: {"description":"VOC","evidences":[{"source":"PROSITE-ProRule","id":"PRU01163","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU01163","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01163","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"12224946","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1LQK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LQP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1NKI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1NNR","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01163","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1fro |
| Chain | Residue | Details |
| A | GLU110 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1fro |
| Chain | Residue | Details |
| B | GLU110 |
