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1LPC

HIGH RESOLUTION STRUCTURE OF RECOMBINANT DIANTHIN ANTIVIRAL PROTEIN-POTENT ANTI-HIV AGENT (COMPLEX WITH CYCLIC AMP)

Functional Information from GO Data
ChainGOidnamespacecontents
A0006952biological_processdefense response
A0016787molecular_functionhydrolase activity
A0017148biological_processnegative regulation of translation
A0030598molecular_functionrRNA N-glycosylase activity
A0035821biological_processmodulation of process of another organism
A0050688biological_processregulation of defense response to virus
A0090729molecular_functiontoxin activity
Functional Information from PDB Data
site_idAC1
Number of Residues13
DetailsBINDING SITE FOR RESIDUE CMP A 901
ChainResidue
ALEU72
AVAL207
ATRP209
ASER210
AHOH950
ATYR73
AVAL74
AGLU119
ATYR121
AILE172
AGLU177
AARG180
AGLN206

Functional Information from PROSITE/UniProt
site_idPS00275
Number of Residues17
DetailsSHIGA_RICIN Shiga/ricin ribosomal inactivating toxins active site signature. IqMTaEAARFRyIQnlV
ChainResidueDetails
AILE172-VAL188

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:P20656
ChainResidueDetails
AGLU177

Catalytic Information from CSA
site_idCSA1
Number of Residues2
DetailsAnnotated By Reference To The Literature 1abr
ChainResidueDetails
AGLU177
AARG180

226707

PDB entries from 2024-10-30

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