Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004590 | molecular_function | orotidine-5'-phosphate decarboxylase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| A | 0006221 | biological_process | pyrimidine nucleotide biosynthetic process |
| A | 0016831 | molecular_function | carboxy-lyase activity |
| A | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
| B | 0004590 | molecular_function | orotidine-5'-phosphate decarboxylase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| B | 0006221 | biological_process | pyrimidine nucleotide biosynthetic process |
| B | 0016831 | molecular_function | carboxy-lyase activity |
| B | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE BU2 A 5001 |
| Chain | Residue |
| A | ASP70 |
| A | LYS72 |
| A | LEU123 |
| A | VAL155 |
| A | XMP2001 |
| A | HOH3015 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE BU2 B 5002 |
| Chain | Residue |
| B | ILE1096 |
| B | VAL1155 |
| B | XMP2002 |
| B | LYS1042 |
| B | ASP1070 |
| B | LYS1072 |
| site_id | AC3 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE XMP A 2001 |
| Chain | Residue |
| A | ALA18 |
| A | ASP20 |
| A | LYS42 |
| A | ASP70 |
| A | MET126 |
| A | SER127 |
| A | SER158 |
| A | PRO180 |
| A | GLY202 |
| A | ARG203 |
| A | HOH3009 |
| A | HOH3011 |
| A | HOH3012 |
| A | HOH3015 |
| A | HOH3085 |
| A | BU25001 |
| B | ILE1076 |
| B | HOH3066 |
| site_id | AC4 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE XMP B 2002 |
| Chain | Residue |
| A | ILE76 |
| B | ALA1018 |
| B | ASP1020 |
| B | LYS1042 |
| B | ASP1070 |
| B | SER1127 |
| B | PRO1157 |
| B | SER1158 |
| B | PRO1180 |
| B | GLY1202 |
| B | ARG1203 |
| B | HOH3059 |
| B | HOH3112 |
| B | HOH3155 |
| B | HOH3159 |
| B | BU25002 |
Functional Information from PROSITE/UniProt
| site_id | PS00156 |
| Number of Residues | 14 |
| Details | OMPDECASE Orotidine 5'-phosphate decarboxylase active site. IIaDfKvaDIPeTN |
| Chain | Residue | Details |
| A | ILE67-ASN80 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor |
| Chain | Residue | Details |
| A | LYS72 | |
| B | LYS1072 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 14 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | ASP20 | |
| B | ASP1070 | |
| B | SER1127 | |
| B | PRO1180 | |
| B | GLY1202 | |
| B | ARG1203 | |
| A | LYS42 | |
| A | ASP70 | |
| A | SER127 | |
| A | PRO180 | |
| A | GLY202 | |
| A | ARG203 | |
| B | ASP1020 | |
| B | LYS1042 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1dbt |
| Chain | Residue | Details |
| A | LYS72 | |
| A | ASP70 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1dbt |
| Chain | Residue | Details |
| B | ASP1070 | |
| B | LYS1072 | |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1dbt |
| Chain | Residue | Details |
| A | LYS42 | |
| A | ASP75 | |
| A | LYS72 | |
| A | ASP70 | |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1dbt |
| Chain | Residue | Details |
| B | ASP1070 | |
| B | ASP1075 | |
| B | LYS1072 | |
| B | LYS1042 | |
