Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0001533 | cellular_component | cornified envelope |
A | 0004252 | molecular_function | serine-type endopeptidase activity |
A | 0005515 | molecular_function | protein binding |
A | 0005576 | cellular_component | extracellular region |
A | 0005615 | cellular_component | extracellular space |
A | 0005634 | cellular_component | nucleus |
A | 0005654 | cellular_component | nucleoplasm |
A | 0005730 | cellular_component | nucleolus |
A | 0005737 | cellular_component | cytoplasm |
A | 0005739 | cellular_component | mitochondrion |
A | 0005783 | cellular_component | endoplasmic reticulum |
A | 0006508 | biological_process | proteolysis |
A | 0007417 | biological_process | central nervous system development |
A | 0008233 | molecular_function | peptidase activity |
A | 0008236 | molecular_function | serine-type peptidase activity |
A | 0009611 | biological_process | response to wounding |
A | 0010975 | biological_process | regulation of neuron projection development |
A | 0016540 | biological_process | protein autoprocessing |
A | 0030141 | cellular_component | secretory granule |
A | 0030574 | biological_process | collagen catabolic process |
A | 0031965 | cellular_component | nuclear membrane |
A | 0042246 | biological_process | tissue regeneration |
A | 0042445 | biological_process | hormone metabolic process |
A | 0042552 | biological_process | myelination |
A | 0042982 | biological_process | amyloid precursor protein metabolic process |
A | 0045171 | cellular_component | intercellular bridge |
A | 0045595 | biological_process | regulation of cell differentiation |
A | 0045745 | biological_process | positive regulation of G protein-coupled receptor signaling pathway |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE MG A 443 |
Chain | Residue |
A | HOH341 |
A | HOH357 |
A | HOH419 |
A | HOH424 |
A | HOH433 |
A | HOH434 |
site_id | AC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE BEN A 299 |
Chain | Residue |
A | GLY216 |
A | ASN217 |
A | GLY226 |
A | ASP189 |
A | SER190 |
A | TRP215 |
Functional Information from PROSITE/UniProt
site_id | PS00134 |
Number of Residues | 6 |
Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
Chain | Residue | Details |
A | LEU53-CYS58 | |
site_id | PS00135 |
Number of Residues | 12 |
Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPLV |
Chain | Residue | Details |
A | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | HIS57 | |
A | ASP102 | |
A | SER195 | |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | SITE: Cleavage; by autolysis |
Chain | Residue | Details |
A | ARG76 | |
site_id | SWS_FT_FI3 |
Number of Residues | 1 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
Chain | Residue | Details |
A | ASN132 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
A | ASP102 | |
A | HIS57 | |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
A | SER195 | |
A | GLY196 | |
site_id | CSA3 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
A | SER195 | |
A | GLY193 | |
site_id | CSA4 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
A | ASP102 | |
A | SER195 | |
A | HIS57 | |
site_id | CSA5 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
A | ASP102 | |
A | SER195 | |
A | GLY193 | |
A | HIS57 | |
site_id | CSA6 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
A | ASP102 | |
A | SER195 | |
A | HIS57 | |
A | GLY196 | |
site_id | CSA7 |
Number of Residues | 5 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
A | SER195 | |
A | GLY193 | |
A | HIS57 | |
A | SER214 | |
A | ASP93 | |
site_id | CSA8 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1a0j |
Chain | Residue | Details |
A | SER195 | |
A | GLY193 | |
A | ASP95 | |
A | HIS57 | |