Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004001 | molecular_function | adenosine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005829 | cellular_component | cytosol |
| A | 0006144 | biological_process | purine nucleobase metabolic process |
| A | 0006166 | biological_process | purine ribonucleoside salvage |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0034654 | biological_process | nucleobase-containing compound biosynthetic process |
| A | 0044209 | biological_process | AMP salvage |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0055086 | biological_process | nucleobase-containing small molecule metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 999 |
| Chain | Residue |
| A | ARG136 |
| A | ASN223 |
| A | GLY317 |
| A | HOH1034 |
| A | HOH1056 |
| A | HOH1098 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 899 |
| Chain | Residue |
| A | ASP35 |
| A | LYS80 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE ADN A 699 |
| Chain | Residue |
| A | ILE22 |
| A | ASP24 |
| A | GLY68 |
| A | GLY69 |
| A | SER70 |
| A | ASN73 |
| A | THR140 |
| A | TYR169 |
| A | ASP318 |
| A | HOH1038 |
| A | HOH1040 |
| A | HOH1041 |
| A | HOH1056 |
| A | ASN20 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ADN A 799 |
| Chain | Residue |
| A | GLY280 |
| A | HIS281 |
| A | VAL302 |
| A | ASN342 |
| A | ALA345 |
| A | GLN346 |
| A | HOH1032 |
| A | HOH1076 |
Functional Information from PROSITE/UniProt
| site_id | PS00584 |
| Number of Residues | 14 |
| Details | PFKB_KINASES_2 pfkB family of carbohydrate kinases signature 2. DTnGAGDafvGGFL |
| Chain | Residue | Details |
| A | ASP312-LEU325 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"10669608","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10669608","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"10794412","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1DGM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LII","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LIK","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10669608","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1LII","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LIK","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10669608","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1LIK","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10669608","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1LII","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10794412","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1DGM","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1lio |
| Chain | Residue | Details |
| A | ARG136 | |
| A | ASP318 |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1lio |
| Chain | Residue | Details |
| A | ALA316 | |
| A | GLY317 | |
| A | GLY315 | |
| A | ASP318 |
| site_id | MCSA1 |
| Number of Residues | 2 |
| Details | M-CSA 209 |
| Chain | Residue | Details |
| A | ARG136 | electrostatic stabiliser, hydrogen bond donor |
| A | ASP318 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
