1LH0
Crystal Structure of Salmonella typhimurium OMP Synthase in Complex with MGPRPP and Orotate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004588 | molecular_function | orotate phosphoribosyltransferase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| A | 0006221 | biological_process | pyrimidine nucleotide biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016757 | molecular_function | glycosyltransferase activity |
| A | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
| A | 0046132 | biological_process | pyrimidine ribonucleoside biosynthetic process |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0004588 | molecular_function | orotate phosphoribosyltransferase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| B | 0006221 | biological_process | pyrimidine nucleotide biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016757 | molecular_function | glycosyltransferase activity |
| B | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
| B | 0046132 | biological_process | pyrimidine ribonucleoside biosynthetic process |
Functional Information from PROSITE/UniProt
| site_id | PS00103 |
| Number of Residues | 13 |
| Details | PUR_PYR_PR_TRANSFER Purine/pyrimidine phosphoribosyl transferases signature. VMLVDDVITAGtA |
| Chain | Residue | Details |
| A | VAL1120-ALA1132 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 22 |
| Details | Binding site: {"description":"in other chain","evidences":[{"source":"PubMed","id":"7545004","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"7545004","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oro |
| Chain | Residue | Details |
| A | LYS1103 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1oro |
| Chain | Residue | Details |
| A | ASP1104 | |
| A | LYS1073 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oro |
| Chain | Residue | Details |
| B | LYS2073 |
