1LB3

Structure of recombinant mouse L chain ferritin at 1.2 A resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005506	molecular_function	iron ion binding
A	0005515	molecular_function	protein binding
A	0005576	cellular_component	extracellular region
A	0005737	cellular_component	cytoplasm
A	0005764	cellular_component	lysosome
A	0005776	cellular_component	autophagosome
A	0006826	biological_process	iron ion transport
A	0006879	biological_process	intracellular iron ion homeostasis
A	0008199	molecular_function	ferric iron binding
A	0031410	cellular_component	cytoplasmic vesicle
A	0044754	cellular_component	autolysosome
A	0046872	molecular_function	metal ion binding
A	0070288	cellular_component	ferritin complex
A	0071682	cellular_component	endocytic vesicle lumen

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 187

Chain	Residue
A	GLN10
A	ASN11
A	HOH204
A	HOH209
A	HOH310
A	HOH372

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 188

Chain	Residue
A	ARG124
A	SER13
A	THR14
A	GLU15

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD A 717

Chain	Residue
A	ASP84
A	ASP84
A	GLN86
A	GLN86

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CD A 718

Chain	Residue
A	GLU60
A	GLU64
A	HOH505
A	HOH506
A	CD722

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CD A 722

Chain	Residue
A	GLU61
A	GLU64
A	HOH505
A	HOH506
A	CD718

---

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CD A 723

Chain	Residue
A	GLU57
A	GLU60
A	HOH507

---

site_id	AC7
Number of Residues	19
Details	BINDING SITE FOR RESIDUE CD A 715

Chain	Residue
A	ASP131
A	ASP131
A	ASP131
A	SER135
A	HOH508
A	HOH508
A	HOH508
A	HOH509
A	HOH509
A	HOH509
A	HOH510
A	HOH510
A	HOH510
A	HOH511
A	HOH511
A	HOH511
A	HOH512
A	HOH512
A	HOH512

---

site_id	AC8
Number of Residues	11
Details	BINDING SITE FOR RESIDUE CD A 716

Chain	Residue
A	GLU134
A	GLU134
A	GLU134
A	HOH452
A	HOH513
A	HOH513
A	HOH513
A	HOH514
A	HOH514
A	HOH515
A	HOH520

---

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CD A 719

Chain	Residue
A	HIS136
A	HOH409
A	HOH516
A	HOH517
A	HOH518

---

site_id	BC1
Number of Residues	11
Details	BINDING SITE FOR RESIDUE CD A 720

Chain	Residue
A	HIS118
A	CYS130
A	GLU134
A	HOH435
A	HOH452
A	HOH513
A	HOH515
A	HOH519
A	HOH519
A	HOH520
A	HOH521

---

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CD A 721

Chain	Residue
A	HIS53
A	GLU57
A	HOH522
A	HOH523
A	HOH524

---

site_id	BC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A 724

Chain	Residue
A	GLU49
A	LYS147
A	ASN150
A	ARG180
A	HOH239
A	HOH348
A	HOH349
A	HOH380

---

site_id	BC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A 189

Chain	Residue
A	PHE39
A	ARG56
A	GLU67
A	ARG68
A	HOH229
A	HOH250
A	HOH442
A	HOH443

---

Functional Information from PROSITE/UniProt

site_id	PS00204
Number of Residues	21
Details	FERRITIN_2 Ferritin iron-binding regions signature 2. DphLCDFLEshYLdkevklIK

Chain	Residue	Details
A	ASP126-LYS146

---

site_id	PS00540
Number of Residues	19
Details	FERRITIN_1 Ferritin iron-binding regions signature 1. EkREgaERLLefQNdRgGR

Chain	Residue	Details
A	GLU61-ARG79

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00085

Chain	Residue	Details
A	LEU58
A	GLU61
A	LYS62
A	GLY65
A	ARG68

---