1LA6
The crystal structure of Trematomus newnesi hemoglobin in a partial hemichrome state
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004601 | molecular_function | peroxidase activity |
| A | 0005344 | molecular_function | oxygen carrier activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0005833 | cellular_component | hemoglobin complex |
| A | 0015671 | biological_process | oxygen transport |
| A | 0019825 | molecular_function | oxygen binding |
| A | 0020037 | molecular_function | heme binding |
| A | 0031720 | molecular_function | haptoglobin binding |
| A | 0031838 | cellular_component | haptoglobin-hemoglobin complex |
| A | 0042744 | biological_process | hydrogen peroxide catabolic process |
| A | 0043177 | molecular_function | organic acid binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0072562 | cellular_component | blood microparticle |
| A | 0098869 | biological_process | cellular oxidant detoxification |
| B | 0004601 | molecular_function | peroxidase activity |
| B | 0005344 | molecular_function | oxygen carrier activity |
| B | 0005833 | cellular_component | hemoglobin complex |
| B | 0015671 | biological_process | oxygen transport |
| B | 0019825 | molecular_function | oxygen binding |
| B | 0020037 | molecular_function | heme binding |
| B | 0031720 | molecular_function | haptoglobin binding |
| B | 0031838 | cellular_component | haptoglobin-hemoglobin complex |
| B | 0042744 | biological_process | hydrogen peroxide catabolic process |
| B | 0043177 | molecular_function | organic acid binding |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0072562 | cellular_component | blood microparticle |
| B | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE HEM A 143 |
| Chain | Residue |
| A | TYR42 |
| A | PHE99 |
| A | LEU102 |
| A | ASN103 |
| A | CMO144 |
| A | HIS45 |
| A | HIS59 |
| A | LYS62 |
| A | GLN87 |
| A | HIS88 |
| A | LEU92 |
| A | VAL94 |
| A | ASN98 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CMO A 144 |
| Chain | Residue |
| A | HIS59 |
| A | VAL63 |
| A | HEM143 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE HEM B 147 |
| Chain | Residue |
| B | TYR41 |
| B | PHE42 |
| B | HIS63 |
| B | LYS66 |
| B | LEU91 |
| B | HIS92 |
| B | LEU96 |
| B | ASN102 |
| B | PHE103 |
| B | LEU141 |
| B | HOH269 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | BINDING: distal binding residue => ECO:0000269|PubMed:12093902, ECO:0007744|PDB:1LA6 |
| Chain | Residue | Details |
| B | HIS63 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: proximal binding residue => ECO:0000269|PubMed:12093902, ECO:0007744|PDB:1LA6, ECO:0007744|PDB:1T1N, ECO:0007744|PDB:3D1K, ECO:0007744|PDB:3NFE, ECO:0007744|PDB:3NG6 |
| Chain | Residue | Details |
| B | HIS92 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: N-acetylserine => ECO:0000269|PubMed:8144556 |
| Chain | Residue | Details |
| A | SER1 |
