1LA0

Solution Structure of Calcium Saturated Cardiac Troponin C in the Troponin C-Troponin I Complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003009	biological_process	skeletal muscle contraction
A	0005509	molecular_function	calcium ion binding
A	0008092	molecular_function	cytoskeletal protein binding
A	0031013	molecular_function	troponin I binding
A	0046872	molecular_function	metal ion binding
A	0048306	molecular_function	calcium-dependent protein binding
A	0060048	biological_process	cardiac muscle contraction
A	1990584	cellular_component	cardiac Troponin complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA A 162

Chain	Residue
A	ASP65
A	ASP67
A	THR71
A	GLU76

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 163

Chain	Residue
A	GLU116
A	ASP105
A	LYS106
A	ASN107
A	ASP109
A	TYR111

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 164

Chain	Residue
A	ASP141
A	ASN143
A	ASN144
A	ASP145
A	ARG147
A	GLU152

---

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DEDGSGTVDfdEF

Chain	Residue	Details
A	ASP65-PHE77
A	ASP105-LEU117
A	ASP141-PHE153

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	35
Details	Domain: {"description":"EF-hand 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	35
Details	Domain: {"description":"EF-hand 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	35
Details	Domain: {"description":"EF-hand 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	33
Details	Domain: {"description":"EF-hand 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	15
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Modified residue: {"description":"N-acetylmethionine","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---