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1L9V

Non Structural protein encoded by gene segment 8 of rotavirus (NSP2), an NTPase, ssRNA binding and nucleic acid helix-destabilizing protein

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0003723molecular_functionRNA binding
A0004550molecular_functionnucleoside diphosphate kinase activity
A0005524molecular_functionATP binding
A0016787molecular_functionhydrolase activity
A0016817molecular_functionhydrolase activity, acting on acid anhydrides
A0017111molecular_functionribonucleoside triphosphate phosphatase activity
A0019079biological_processviral genome replication
A0030430cellular_componenthost cell cytoplasm
A0046872molecular_functionmetal ion binding
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues36
DetailsRegion: {"description":"RNA-binding","evidences":[{"source":"HAMAP-Rule","id":"MF_04089","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"22811529","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues1
DetailsActive site: {"description":"For NTPase and RTPase activities","evidences":[{"source":"HAMAP-Rule","id":"MF_04089","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"17804496","evidenceCode":"ECO:0000305"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues6
DetailsBinding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_04089","evidenceCode":"ECO:0000255"},{"source":"PDB","id":"2R7P","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

240971

PDB entries from 2025-08-27

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