1L5J

CRYSTAL STRUCTURE OF E. COLI ACONITASE B.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0003729	molecular_function	mRNA binding
A	0003730	molecular_function	mRNA 3'-UTR binding
A	0003994	molecular_function	aconitate hydratase activity
A	0005515	molecular_function	protein binding
A	0005829	cellular_component	cytosol
A	0006097	biological_process	glyoxylate cycle
A	0006099	biological_process	tricarboxylic acid cycle
A	0006417	biological_process	regulation of translation
A	0016829	molecular_function	lyase activity
A	0019629	biological_process	propionate catabolic process, 2-methylcitrate cycle
A	0046872	molecular_function	metal ion binding
A	0047456	molecular_function	2-methylisocitrate dehydratase activity
A	0051536	molecular_function	iron-sulfur cluster binding
A	0051539	molecular_function	4 iron, 4 sulfur cluster binding
B	0003723	molecular_function	RNA binding
B	0003729	molecular_function	mRNA binding
B	0003730	molecular_function	mRNA 3'-UTR binding
B	0003994	molecular_function	aconitate hydratase activity
B	0005515	molecular_function	protein binding
B	0005829	cellular_component	cytosol
B	0006097	biological_process	glyoxylate cycle
B	0006099	biological_process	tricarboxylic acid cycle
B	0006417	biological_process	regulation of translation
B	0016829	molecular_function	lyase activity
B	0019629	biological_process	propionate catabolic process, 2-methylcitrate cycle
B	0046872	molecular_function	metal ion binding
B	0047456	molecular_function	2-methylisocitrate dehydratase activity
B	0051536	molecular_function	iron-sulfur cluster binding
B	0051539	molecular_function	4 iron, 4 sulfur cluster binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	BINDING SITE FOR RESIDUE TRA A 866

Chain	Residue
A	ARG191
A	MET773
A	ARG791
A	ARG796
A	F3S868
A	SER244
A	SER245
A	ARG246
A	GLN414
A	THR416
A	THR417
A	ASP497
A	SER498

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site_id	AC2
Number of Residues	12
Details	BINDING SITE FOR RESIDUE TRA B 867

Chain	Residue
B	ARG191
B	SER244
B	SER245
B	ARG246
B	GLN414
B	THR416
B	THR417
B	ASP497
B	SER498
B	ARG791
B	ARG796
B	F3S869

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site_id	AC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE F3S A 868

Chain	Residue
A	HIS444
A	HIS480
A	HIS499
A	SER709
A	CYS710
A	CYS769
A	CYS772
A	THR790
A	TRA866
A	HOH874

---

site_id	AC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE F3S B 869

Chain	Residue
B	HIS444
B	HIS480
B	HIS499
B	SER709
B	CYS710
B	CYS769
B	CYS772
B	THR790
B	TRA867

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Functional Information from PROSITE/UniProt

site_id	PS00450
Number of Residues	18
Details	ACONITASE_1 Aconitase family signature 1. IdeVfIGSCmTNIghfrA

Chain	Residue	Details
A	ILE702-ALA719

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site_id	PS01244
Number of Residues	14
Details	ACONITASE_2 Aconitase family signature 2. GarIeipGCSLCMG

Chain	Residue	Details
A	GLY761-GLY774

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	22
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11992126","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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