1L3E
NMR Structures of the HIF-1alpha CTAD/p300 CH1 Complex
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 202 |
| Chain | Residue |
| B | HIS125 |
| B | CYS129 |
| B | CYS142 |
| B | CYS147 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 203 |
| Chain | Residue |
| B | HIS156 |
| B | CYS160 |
| B | CYS166 |
| B | CYS171 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 204 |
| Chain | Residue |
| B | HIS180 |
| B | CYS184 |
| B | CYS189 |
| B | CYS192 |
| site_id | Zn1 |
| Number of Residues | 4 |
| Details | Zinc coordinate site 1 |
| Chain | Residue |
| B | HIS125 |
| B | CYS129 |
| B | CYS142 |
| B | CYS147 |
| site_id | Zn2 |
| Number of Residues | 4 |
| Details | Zinc coordinate site 2 |
| Chain | Residue |
| B | HIS156 |
| B | CYS160 |
| B | CYS166 |
| B | CYS171 |
| site_id | Zn3 |
| Number of Residues | 4 |
| Details | Zinc coordinate site 3 |
| Chain | Residue |
| B | CYS184 |
| B | CYS189 |
| B | CYS192 |
| B | HIS180 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 40 |
| Details | Region: {"description":"CTAD","evidences":[{"source":"PubMed","id":"10202154","evidenceCode":"ECO:0000303"},{"source":"PubMed","id":"9235919","evidenceCode":"ECO:0000303"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"S-nitrosocysteine","evidences":[{"source":"PubMed","id":"12914934","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"(3S)-3-hydroxyasparagine","evidences":[{"source":"PubMed","id":"12080085","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 86 |
| Details | Zinc finger: {"description":"TAZ-type 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00203","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11959990","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12778114","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"18995842","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
