1KZ6

Mutant enzyme W63Y/L119F Lumazine Synthase from S.pombe

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000906	molecular_function	6,7-dimethyl-8-ribityllumazine synthase activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005758	cellular_component	mitochondrial intermembrane space
A	0009231	biological_process	riboflavin biosynthetic process
A	0009349	cellular_component	riboflavin synthase complex
A	1902444	molecular_function	riboflavin binding
B	0000906	molecular_function	6,7-dimethyl-8-ribityllumazine synthase activity
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005758	cellular_component	mitochondrial intermembrane space
B	0009231	biological_process	riboflavin biosynthetic process
B	0009349	cellular_component	riboflavin synthase complex
B	1902444	molecular_function	riboflavin binding
C	0000906	molecular_function	6,7-dimethyl-8-ribityllumazine synthase activity
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005737	cellular_component	cytoplasm
C	0005758	cellular_component	mitochondrial intermembrane space
C	0009231	biological_process	riboflavin biosynthetic process
C	0009349	cellular_component	riboflavin synthase complex
C	1902444	molecular_function	riboflavin binding
D	0000906	molecular_function	6,7-dimethyl-8-ribityllumazine synthase activity
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005737	cellular_component	cytoplasm
D	0005758	cellular_component	mitochondrial intermembrane space
D	0009231	biological_process	riboflavin biosynthetic process
D	0009349	cellular_component	riboflavin synthase complex
D	1902444	molecular_function	riboflavin binding
E	0000906	molecular_function	6,7-dimethyl-8-ribityllumazine synthase activity
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005737	cellular_component	cytoplasm
E	0005758	cellular_component	mitochondrial intermembrane space
E	0009231	biological_process	riboflavin biosynthetic process
E	0009349	cellular_component	riboflavin synthase complex
E	1902444	molecular_function	riboflavin binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE PO4 B 1001

Chain	Residue
A	ARG133
B	SER91
B	THR92
B	HIS94
B	HOH1003
B	HOH1008
B	HOH1010
B	HOH1018

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PO4 E 1002

Chain	Residue
E	GLY90
E	SER91
E	THR92
E	HIS94
E	HOH1005
D	ARG133

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PO4 C 1003

Chain	Residue
B	ARG133
C	GLY90
C	SER91
C	THR92
C	HOH1005
C	HOH1024

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PO4 A 1004

Chain	Residue
A	SER91
A	THR92
A	HOH1005
E	ARG133

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PO4 D 1005

Chain	Residue
C	ARG133
D	SER91
D	THR92
D	HOH1006
D	HOH1007

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	Active site: {"description":"Proton donor","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	30
Details	Binding site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	10
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1rvv

Chain	Residue	Details
A	HIS94

---

site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1rvv

Chain	Residue	Details
B	HIS94

---

site_id	CSA3
Number of Residues	1
Details	Annotated By Reference To The Literature 1rvv

Chain	Residue	Details
C	HIS94

---

site_id	CSA4
Number of Residues	1
Details	Annotated By Reference To The Literature 1rvv

Chain	Residue	Details
D	HIS94

---

site_id	CSA5
Number of Residues	1
Details	Annotated By Reference To The Literature 1rvv

Chain	Residue	Details
E	HIS94

---