1KWT
Rat mannose binding protein A (native, MPD)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001867 | biological_process | complement activation, lectin pathway |
| A | 0005537 | molecular_function | mannose binding |
| B | 0001867 | biological_process | complement activation, lectin pathway |
| B | 0005537 | molecular_function | mannose binding |
| C | 0001867 | biological_process | complement activation, lectin pathway |
| C | 0005537 | molecular_function | mannose binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 501 |
| Chain | Residue |
| A | ASP161 |
| A | GLU165 |
| A | ASP188 |
| A | GLU193 |
| A | ASP194 |
| A | HOH626 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA A 502 |
| Chain | Residue |
| A | ASN205 |
| A | ASP206 |
| A | HOH731 |
| A | HOH732 |
| A | GLU185 |
| A | ASN187 |
| A | GLU193 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 503 |
| Chain | Residue |
| A | GLU84 |
| A | GLU165 |
| A | ASP194 |
| A | HOH643 |
| A | HOH690 |
| A | HOH692 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 504 |
| Chain | Residue |
| A | ASP194 |
| A | SER208 |
| A | CYS209 |
| A | HOH753 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA B 601 |
| Chain | Residue |
| B | ASP161 |
| B | GLU165 |
| B | ASP188 |
| B | GLU193 |
| B | ASP194 |
| B | CA603 |
| B | HOH623 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA B 602 |
| Chain | Residue |
| B | GLU185 |
| B | ASN187 |
| B | GLU193 |
| B | ASN205 |
| B | ASP206 |
| B | HOH707 |
| B | HOH714 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA B 603 |
| Chain | Residue |
| B | GLU165 |
| B | ASP194 |
| B | CA601 |
| B | HOH629 |
| B | HOH644 |
| B | HOH666 |
| B | HOH687 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 604 |
| Chain | Residue |
| B | ASP194 |
| B | CYS209 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 701 |
| Chain | Residue |
| C | ASP161 |
| C | GLU165 |
| C | ASP188 |
| C | GLU193 |
| C | ASP194 |
| C | HOH724 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA C 702 |
| Chain | Residue |
| C | GLU185 |
| C | ASN187 |
| C | GLU193 |
| C | ASN205 |
| C | ASP206 |
| C | HOH811 |
| C | HOH819 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 703 |
| Chain | Residue |
| C | GLU84 |
| C | GLU165 |
| C | ASP194 |
| C | HOH717 |
| C | HOH718 |
| C | HOH742 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA A 606 |
| Chain | Residue |
| A | HOH724 |
| A | HOH745 |
| B | GLU93 |
| B | HOH653 |
| site_id | BC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL C 704 |
| Chain | Residue |
| C | ASP194 |
| C | CYS209 |
Functional Information from PROSITE/UniProt
| site_id | PS00615 |
| Number of Residues | 23 |
| Details | C_TYPE_LECTIN_1 C-type lectin domain signature. CVtivdngl.....WNDISCqasht.AVC |
| Chain | Residue | Details |
| A | CYS195-CYS217 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:11850428, ECO:0000269|PubMed:1436090, ECO:0000269|PubMed:7704532, ECO:0000269|PubMed:9033386, ECO:0007744|PDB:1AFA, ECO:0007744|PDB:1AFB, ECO:0007744|PDB:1AFD, ECO:0007744|PDB:1BCH, ECO:0007744|PDB:1BCJ, ECO:0007744|PDB:1FIF, ECO:0007744|PDB:1FIH, ECO:0007744|PDB:1KMB, ECO:0007744|PDB:1KWT, ECO:0007744|PDB:1KWU, ECO:0007744|PDB:1KWV, ECO:0007744|PDB:1KWW, ECO:0007744|PDB:1KWX, ECO:0007744|PDB:1KWY, ECO:0007744|PDB:1KWZ, ECO:0007744|PDB:1KX0, ECO:0007744|PDB:1KX1, ECO:0007744|PDB:1RTM, ECO:0007744|PDB:2KMB, ECO:0007744|PDB:2MSB, ECO:0007744|PDB:3KMB, ECO:0007744|PDB:4KMB |
| Chain | Residue | Details |
| A | ASP161 | |
| C | GLU165 | |
| C | ASP188 | |
| C | ASP194 | |
| A | GLU165 | |
| A | ASP188 | |
| A | ASP194 | |
| B | ASP161 | |
| B | GLU165 | |
| B | ASP188 | |
| B | ASP194 | |
| C | ASP161 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 15 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:11850428, ECO:0000269|PubMed:1436090, ECO:0000269|PubMed:7704532, ECO:0000269|PubMed:9033386, ECO:0007744|PDB:1KMB, ECO:0007744|PDB:1KWT, ECO:0007744|PDB:1KWU, ECO:0007744|PDB:1KWV, ECO:0007744|PDB:1KWW, ECO:0007744|PDB:1KWX, ECO:0007744|PDB:1KWY, ECO:0007744|PDB:1KWZ, ECO:0007744|PDB:1KX0, ECO:0007744|PDB:1KX1, ECO:0007744|PDB:1RTM, ECO:0007744|PDB:2KMB, ECO:0007744|PDB:2MSB, ECO:0007744|PDB:3KMB, ECO:0007744|PDB:4KMB |
| Chain | Residue | Details |
| A | GLU185 | |
| B | ASP206 | |
| C | GLU185 | |
| C | ASN187 | |
| C | GLU193 | |
| C | ASN205 | |
| C | ASP206 | |
| A | ASN187 | |
| A | GLU193 | |
| A | ASN205 | |
| A | ASP206 | |
| B | GLU185 | |
| B | ASN187 | |
| B | GLU193 | |
| B | ASN205 |
