1KWG

Crystal structure of Thermus thermophilus A4 beta-galactosidase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004565	molecular_function	beta-galactosidase activity
A	0005975	biological_process	carbohydrate metabolic process
A	0006012	biological_process	galactose metabolic process
A	0009341	cellular_component	beta-galactosidase complex
A	0016787	molecular_function	hydrolase activity
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CL A 801

Chain	Residue
A	TYR6
A	TYR7
A	TRP11
A	ARG351
A	ARG353

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ACT A 804

Chain	Residue
A	GLY535
A	HOH875
A	HOH927
A	HOH1424

---

site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE ACT A 805

Chain	Residue
A	ARG560

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 806

Chain	Residue
A	CYS106
A	CYS150
A	CYS152
A	CYS155

---

site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MPD A 802

Chain	Residue
A	PRO275

---

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MPD A 803

Chain	Residue
A	ALA433
A	ARG436
A	PRO573
A	GLY577
A	HOH865
A	HOH902
A	HOH984

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton donor"}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Nucleophile"}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"12215416","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	7
Details	Binding site: {}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1cz1

Chain	Residue	Details
A	GLU141
A	ASN241

---