1KV9

Structure at 1.9 A Resolution of a Quinohemoprotein Alcohol Dehydrogenase from Pseudomonas putida HK5

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding
A	0009055	molecular_function	electron transfer activity
A	0016020	cellular_component	membrane
A	0016491	molecular_function	oxidoreductase activity
A	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
A	0020037	molecular_function	heme binding
A	0030288	cellular_component	outer membrane-bounded periplasmic space
A	0042597	cellular_component	periplasmic space
A	0046872	molecular_function	metal ion binding
A	0070968	molecular_function	pyrroloquinoline quinone binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA A 802

Chain	Residue
A	GLU173
A	ASN250
A	ASP295
A	PQQ801

---

site_id	AC2
Number of Residues	24
Details	BINDING SITE FOR RESIDUE PQQ A 801

Chain	Residue
A	THR155
A	GLY170
A	GLY171
A	ALA172
A	GLU173
A	THR230
A	TRP232
A	ASN250
A	ASP295
A	LYS322
A	ASN382
A	TRP383
A	TRP460
A	GLY524
A	VAL525
A	CA802
A	ACN803
A	HOH1114
A	HOH1210
A	GLU59
A	CYS105
A	CYS106
A	VAL109
A	ARG111

---

site_id	AC3
Number of Residues	21
Details	BINDING SITE FOR RESIDUE HEC A 901

Chain	Residue
A	ALA101
A	ARG102
A	PHE590
A	CYS591
A	CYS594
A	HIS595
A	ILE605
A	PRO606
A	LEU608
A	SER611
A	PHE619
A	VAL623
A	LEU631
A	MET633
A	PHE636
A	LEU640
A	HOH1091
A	HOH1139
A	HOH1242
A	HOH1362
A	HOH1514

---

site_id	AC4
Number of Residues	11
Details	BINDING SITE FOR RESIDUE EPE A 804

Chain	Residue
A	TRP48
A	ALA83
A	ALA84
A	SER85
A	TYR515
A	HOH1178
A	HOH1528
A	HOH1614
A	HOH1683
A	HOH1687
A	HOH1735

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ACN A 803

Chain	Residue
A	GLU173
A	ASP295
A	LYS322
A	PRO377
A	PQQ801

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 805

Chain	Residue
A	ASP51
A	LEU52
A	SER543
A	HOH1392
A	HOH1531

---

Functional Information from PROSITE/UniProt

site_id	PS00364
Number of Residues	22
Details	BACTERIAL_PQQ_2 Bacterial quinoprotein dehydrogenases signature 2. WdsmaYDpelDLLYVgtGngSP

Chain	Residue	Details
A	TRP232-PRO253

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	78
Details	Domain: {"description":"Cytochrome c","evidences":[{"source":"PROSITE-ProRule","id":"PRU00433","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"12057198","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	11
Details	Binding site: {"evidences":[{"source":"PubMed","id":"12057198","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1KV9","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"description":"covalent","evidences":[{"source":"PubMed","id":"12057198","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1KV9","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"12057198","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1KV9","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1g72

Chain	Residue	Details
A	ASP295

---