1KSS

Crystal Structure of His505Ala Mutant Flavocytochrome c3 from Shewanella frigidimarina

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0009055	molecular_function	electron transfer activity
A	0009061	biological_process	anaerobic respiration
A	0010181	molecular_function	FMN binding
A	0016491	molecular_function	oxidoreductase activity
A	0016627	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors
A	0019645	biological_process	anaerobic electron transport chain
A	0030288	cellular_component	outer membrane-bounded periplasmic space
A	0042597	cellular_component	periplasmic space
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE NA A 1810

Chain	Residue
A	THR506
A	MET507
A	GLY508
A	GLU534
A	THR536
A	HOH1849

---

site_id	AC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE HEM A 801

Chain	Residue
A	SER73
A	ALA74
A	HIS75
A	HOH1981
A	HOH1997
A	HOH2018
A	HOH2351
A	HOH2907
A	CYS14
A	CYS17
A	HIS18

---

site_id	AC3
Number of Residues	16
Details	BINDING SITE FOR RESIDUE HEM A 802

Chain	Residue
A	LEU4
A	PHE7
A	HIS8
A	GLN12
A	SER16
A	GLN35
A	CYS36
A	CYS39
A	HIS40
A	HIS72
A	TYR94
A	HEM803
A	HOH2319
A	HOH2320
A	HOH2363
A	HOH2569

---

site_id	AC4
Number of Residues	21
Details	BINDING SITE FOR RESIDUE HEM A 803

Chain	Residue
A	HIS40
A	LEU43
A	VAL46
A	HIS52
A	ALA57
A	HIS58
A	VAL66
A	ALA67
A	CYS68
A	CYS71
A	HIS72
A	PHE90
A	ASN91
A	MET92
A	HEM802
A	HEM804
A	HOH1829
A	HOH1942
A	HOH2384
A	HOH2505
A	HOH2746

---

site_id	AC5
Number of Residues	25
Details	BINDING SITE FOR RESIDUE HEM A 804

Chain	Residue
A	HIS54
A	ASN56
A	SER60
A	HIS61
A	PHE62
A	CYS82
A	SER84
A	CYS85
A	HIS86
A	PHE88
A	LEU167
A	GLN338
A	VAL374
A	LYS431
A	LYS434
A	HEM803
A	HOH1834
A	HOH1898
A	HOH1904
A	HOH1913
A	HOH1920
A	HOH1956
A	HOH2050
A	HOH2230
A	HOH2400

---

site_id	AC6
Number of Residues	41
Details	BINDING SITE FOR RESIDUE FAD A 1805

Chain	Residue
A	THR313
A	GLY314
A	GLN338
A	ASP344
A	MET375
A	HIS504
A	GLY533
A	GLU534
A	ARG544
A	GLY547
A	ASN548
A	ALA549
A	ILE550
A	ILE553
A	FUM1806
A	HOH1812
A	HOH1836
A	HOH1844
A	HOH1864
A	HOH1870
A	HOH1940
A	VAL132
A	GLY133
A	GLY135
A	GLY136
A	ALA137
A	GLU156
A	LYS157
A	GLU158
A	GLY162
A	GLY163
A	ASN164
A	ALA165
A	LEU167
A	ALA168
A	ALA169
A	GLY170
A	GLY171
A	ARG277
A	GLY278
A	ALA312

---

site_id	AC7
Number of Residues	10
Details	BINDING SITE FOR RESIDUE FUM A 1806

Chain	Residue
A	GLY170
A	HIS365
A	THR377
A	GLU378
A	ARG402
A	HIS504
A	ARG544
A	GLY546
A	GLY547
A	FAD1805

---

Functional Information from PROSITE/UniProt

site_id	PS00028
Number of Residues	23
Details	ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. Cvs..ChgtLaevaettkHehynaH

Chain	Residue	Details
A	CYS36-HIS58

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"10978153","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"10978153","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1E39","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	7
Details	Binding site: {"description":"covalent","evidences":[{"source":"PubMed","id":"10978153","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1E39","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	8
Details	Binding site: {"description":"covalent","evidences":[{"source":"UniProtKB","id":"P83223","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	17
Details	Binding site: {"evidences":[{"source":"PubMed","id":"10978153","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1E39","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	8
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"UniProtKB","id":"P83223","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	23
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P83223","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	24
Details	Signal: {"evidences":[{"source":"PubMed","id":"1333793","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	1
Details	Active site: {"description":"Proton donor","evidences":[{"source":"UniProtKB","id":"P0C278","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details	Annotated By Reference To The Literature 1d4c

Chain	Residue	Details
A	HIS504
A	ARG544
A	HIS365
A	ARG402

---