1KNC
Structure of AhpD from Mycobacterium tuberculosis, a novel enzyme with thioredoxin-like activity.
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004601 | molecular_function | peroxidase activity |
A | 0005515 | molecular_function | protein binding |
A | 0005829 | cellular_component | cytosol |
A | 0005886 | cellular_component | plasma membrane |
A | 0006979 | biological_process | response to oxidative stress |
A | 0008785 | molecular_function | alkyl hydroperoxide reductase activity |
A | 0015036 | molecular_function | disulfide oxidoreductase activity |
A | 0016209 | molecular_function | antioxidant activity |
A | 0032843 | molecular_function | hydroperoxide reductase activity |
A | 0045454 | biological_process | cell redox homeostasis |
A | 0051920 | molecular_function | peroxiredoxin activity |
A | 0098869 | biological_process | cellular oxidant detoxification |
B | 0004601 | molecular_function | peroxidase activity |
B | 0005515 | molecular_function | protein binding |
B | 0005829 | cellular_component | cytosol |
B | 0005886 | cellular_component | plasma membrane |
B | 0006979 | biological_process | response to oxidative stress |
B | 0008785 | molecular_function | alkyl hydroperoxide reductase activity |
B | 0015036 | molecular_function | disulfide oxidoreductase activity |
B | 0016209 | molecular_function | antioxidant activity |
B | 0032843 | molecular_function | hydroperoxide reductase activity |
B | 0045454 | biological_process | cell redox homeostasis |
B | 0051920 | molecular_function | peroxiredoxin activity |
B | 0098869 | biological_process | cellular oxidant detoxification |
C | 0004601 | molecular_function | peroxidase activity |
C | 0005515 | molecular_function | protein binding |
C | 0005829 | cellular_component | cytosol |
C | 0005886 | cellular_component | plasma membrane |
C | 0006979 | biological_process | response to oxidative stress |
C | 0008785 | molecular_function | alkyl hydroperoxide reductase activity |
C | 0015036 | molecular_function | disulfide oxidoreductase activity |
C | 0016209 | molecular_function | antioxidant activity |
C | 0032843 | molecular_function | hydroperoxide reductase activity |
C | 0045454 | biological_process | cell redox homeostasis |
C | 0051920 | molecular_function | peroxiredoxin activity |
C | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE SO4 B 601 |
Chain | Residue |
B | ARG68 |
B | HIS69 |
site_id | AC2 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE SO4 C 602 |
Chain | Residue |
C | PRO113 |
C | LYS114 |
site_id | AC3 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE SO4 A 603 |
Chain | Residue |
B | PRO113 |
B | HOH626 |
A | PRO113 |
A | LYS114 |
A | HOH650 |
A | HOH676 |
A | HOH677 |
site_id | AC4 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE SO4 B 604 |
Chain | Residue |
B | ARG142 |
site_id | AC5 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE SO4 B 605 |
Chain | Residue |
B | HIS132 |
B | HOH653 |
site_id | AC6 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 B 606 |
Chain | Residue |
B | TYR85 |
B | ARG88 |
B | HOH698 |
site_id | AC7 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE SO4 A 607 |
Chain | Residue |
A | ARG88 |
A | HIS132 |
A | HIS139 |
A | HOH632 |
A | HOH695 |
A | HOH741 |
site_id | AC8 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE SO4 A 608 |
Chain | Residue |
A | GLY89 |
A | HIS132 |
A | HOH640 |
A | HOH641 |
A | HOH647 |
A | HOH687 |
B | ARG94 |
site_id | AC9 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 B 609 |
Chain | Residue |
B | PRO113 |
B | LYS114 |
B | HOH639 |
site_id | BC1 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE SO4 C 610 |
Chain | Residue |
C | ARG68 |
C | HIS69 |
site_id | BC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 C 611 |
Chain | Residue |
C | GLY89 |
C | HIS132 |
C | HOH643 |
C | HOH646 |
site_id | BC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 B 612 |
Chain | Residue |
A | ARG99 |
B | SER64 |
B | ALA65 |
B | ARG68 |
B | HOH712 |
site_id | BC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 A 613 |
Chain | Residue |
A | ARG103 |
A | ASN105 |
A | HOH718 |
A | HOH737 |
C | LYS15 |
site_id | BC5 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE SO4 C 614 |
Chain | Residue |
C | TYR85 |
C | ARG88 |
site_id | BC6 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 C 615 |
Chain | Residue |
B | LYS15 |
C | ARG103 |
C | ASN105 |
site_id | BC7 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 B 616 |
Chain | Residue |
A | LYS15 |
B | ARG103 |
B | ASN105 |
site_id | BC8 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 A 617 |
Chain | Residue |
A | SER64 |
A | ALA65 |
A | HOH624 |
B | HOH695 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 3 |
Details | ACT_SITE: Proton donor => ECO:0000255|HAMAP-Rule:MF_01676, ECO:0000269|PubMed:11914371 |
Chain | Residue | Details |
A | CYS130 | |
B | CYS130 | |
C | CYS130 |
site_id | SWS_FT_FI2 |
Number of Residues | 3 |
Details | ACT_SITE: Cysteine sulfenic acid (-SOH) intermediate => ECO:0000255|HAMAP-Rule:MF_01676, ECO:0000269|PubMed:11914371 |
Chain | Residue | Details |
A | CYS133 | |
B | CYS133 | |
C | CYS133 |