Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004222 | molecular_function | metalloendopeptidase activity |
A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CA A 401 |
Chain | Residue |
A | ASP138 |
A | GLU177 |
A | ASP185 |
A | GLU187 |
A | GLU190 |
A | HOH1320 |
site_id | AC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CA A 402 |
Chain | Residue |
A | GLU190 |
A | HOH1334 |
A | HOH1345 |
A | GLU177 |
A | ASN183 |
A | ASP185 |
site_id | AC3 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CA A 403 |
Chain | Residue |
A | ASP57 |
A | ASP59 |
A | GLN61 |
A | HOH1329 |
A | HOH1331 |
A | HOH1336 |
site_id | AC4 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CA A 404 |
Chain | Residue |
A | TYR193 |
A | THR194 |
A | ILE197 |
A | ASP200 |
A | HOH1324 |
A | HOH1366 |
site_id | AC5 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN A 405 |
Chain | Residue |
A | HIS142 |
A | HIS146 |
A | GLU166 |
A | ASP1317 |
site_id | AC6 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE PHQ A 317 |
Chain | Residue |
A | ASN112 |
A | ALA113 |
A | LEU133 |
A | VAL139 |
A | HIS142 |
A | GLU143 |
A | ILE188 |
A | LEU202 |
A | ASP1317 |
A | HOH1418 |
site_id | AC7 |
Number of Residues | 11 |
Details | BINDING SITE FOR RESIDUE ASP A 1317 |
Chain | Residue |
A | ASN112 |
A | ALA113 |
A | HIS142 |
A | GLU143 |
A | HIS146 |
A | TYR157 |
A | GLU166 |
A | HIS231 |
A | PHQ317 |
A | ZN405 |
A | HOH1498 |
Functional Information from PROSITE/UniProt
site_id | PS00142 |
Number of Residues | 10 |
Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. VVAHELTHAV |
Chain | Residue | Details |
A | VAL139-VAL148 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 3 |
Details | BINDING: |
Chain | Residue | Details |
A | VAL289 | |
A | SER291 | |
A | THR293 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1tlp |
Chain | Residue | Details |
A | HIS231 | |
A | GLU143 | |
site_id | MCSA1 |
Number of Residues | |
Details | M-CSA 176 |