1KIJ
Crystal structure of the 43K ATPase domain of Thermus thermophilus gyrase B in complex with novobiocin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006265 | biological_process | DNA topological change |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006265 | biological_process | DNA topological change |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE NOV A 400 |
| Chain | Residue |
| A | ASN45 |
| A | ILE93 |
| A | LYS102 |
| A | VAL117 |
| A | ARG135 |
| A | THR166 |
| A | HOH507 |
| A | HOH646 |
| A | HOH732 |
| A | HOH909 |
| A | ASP48 |
| A | GLU49 |
| A | ASP72 |
| A | ARG75 |
| A | GLY76 |
| A | ILE77 |
| A | PRO78 |
| A | ASP80 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE NOV B 444 |
| Chain | Residue |
| A | ILE10 |
| B | ASN45 |
| B | ASP48 |
| B | GLU49 |
| B | ASP72 |
| B | ARG75 |
| B | ILE77 |
| B | PRO78 |
| B | ASP80 |
| B | ARG135 |
| B | THR166 |
| B | HOH520 |
| B | HOH539 |
| B | HOH591 |
| B | HOH723 |
| B | HOH755 |
| B | HOH894 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE FMT A 401 |
| Chain | Residue |
| A | HOH792 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FMT B 441 |
| Chain | Residue |
| B | ASN294 |
| B | HOH821 |
| B | HOH823 |
| B | HOH915 |
