1KI0
The X-ray Structure of Human Angiostatin
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE BCN A 335 |
| Chain | Residue |
| A | ARG115 |
| A | HOH548 |
| A | HOH571 |
| A | HOH636 |
| A | HIS198 |
| A | GLY199 |
| A | ILE201 |
| A | GLU221 |
| A | TRP225 |
| A | PHE227 |
| A | ARG234 |
| A | TRP235 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE BCN A 336 |
| Chain | Residue |
| A | ARG117 |
| A | ASP137 |
| A | ASP139 |
| A | TRP144 |
| A | ARG153 |
| A | TYR154 |
| A | THR287 |
| A | HOH711 |
| A | HOH725 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE BCN A 337 |
| Chain | Residue |
| A | ARG290 |
| A | LYS311 |
| A | TRP315 |
| A | HIS317 |
| A | ARG324 |
| A | TRP325 |
| A | HOH516 |
| A | HOH839 |
Functional Information from PROSITE/UniProt
| site_id | PS00021 |
| Number of Residues | 14 |
| Details | KRINGLE_1 Kringle domain signature. YCRNpdndpqgpWC |
| Chain | Residue | Details |
| A | TYR132-CYS145 | |
| A | TYR214-CYS226 | |
| A | TYR304-CYS316 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 78 |
| Details | Domain: {"description":"Kringle 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00121","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 78 |
| Details | Domain: {"description":"Kringle 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00121","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 77 |
| Details | Domain: {"description":"Kringle 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00121","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 19 |
| Details | Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Site: {"description":"Interacts with fibrin"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"O-linked (GalNAc...) serine","featureId":"CAR_000016","evidences":[{"source":"PubMed","id":"3356193","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9054441","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","featureId":"CAR_000017","evidences":[{"source":"PubMed","id":"18780401","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"3356193","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
