1KCX

X-ray structure of NYSGRC target T-45

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004157	molecular_function	dihydropyrimidinase activity
A	0005737	cellular_component	cytoplasm
A	0005813	cellular_component	centrosome
A	0005819	cellular_component	spindle
A	0005829	cellular_component	cytosol
A	0005856	cellular_component	cytoskeleton
A	0006208	biological_process	pyrimidine nucleobase catabolic process
A	0010977	biological_process	negative regulation of neuron projection development
A	0015629	cellular_component	actin cytoskeleton
A	0016787	molecular_function	hydrolase activity
A	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
A	0016812	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
A	0030425	cellular_component	dendrite
A	0030426	cellular_component	growth cone
A	0030496	cellular_component	midbody
A	0031005	molecular_function	filamin binding
A	0042802	molecular_function	identical protein binding
A	0042995	cellular_component	cell projection
A	0043025	cellular_component	neuronal cell body
A	0043204	cellular_component	perikaryon
A	0051219	molecular_function	phosphoprotein binding
A	0071526	biological_process	semaphorin-plexin signaling pathway
A	0098793	cellular_component	presynapse
A	0098794	cellular_component	postsynapse
A	0150052	biological_process	regulation of postsynapse assembly
B	0004157	molecular_function	dihydropyrimidinase activity
B	0005737	cellular_component	cytoplasm
B	0005813	cellular_component	centrosome
B	0005819	cellular_component	spindle
B	0005829	cellular_component	cytosol
B	0005856	cellular_component	cytoskeleton
B	0006208	biological_process	pyrimidine nucleobase catabolic process
B	0010977	biological_process	negative regulation of neuron projection development
B	0015629	cellular_component	actin cytoskeleton
B	0016787	molecular_function	hydrolase activity
B	0016810	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
B	0016812	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B	0030425	cellular_component	dendrite
B	0030426	cellular_component	growth cone
B	0030496	cellular_component	midbody
B	0031005	molecular_function	filamin binding
B	0042802	molecular_function	identical protein binding
B	0042995	cellular_component	cell projection
B	0043025	cellular_component	neuronal cell body
B	0043204	cellular_component	perikaryon
B	0051219	molecular_function	phosphoprotein binding
B	0071526	biological_process	semaphorin-plexin signaling pathway
B	0098793	cellular_component	presynapse
B	0098794	cellular_component	postsynapse
B	0150052	biological_process	regulation of postsynapse assembly

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Motif: {"description":"Required for interaction with FLNA","evidences":[{"source":"UniProtKB","id":"Q14194","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Modified residue: {"description":"Phosphothreonine; by AURKA","evidences":[{"source":"UniProtKB","id":"Q14194","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"3'-nitrotyrosine","evidences":[{"source":"PubMed","id":"16800626","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1j79

Chain	Residue	Details
A	GLY332

---

site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1j79

Chain	Residue	Details
B	GLY332

---