1KB0

Crystal Structure of Quinohemoprotein Alcohol Dehydrogenase from Comamonas testosteroni

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding
A	0009055	molecular_function	electron transfer activity
A	0016020	cellular_component	membrane
A	0016491	molecular_function	oxidoreductase activity
A	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
A	0020037	molecular_function	heme binding
A	0030288	cellular_component	outer membrane-bounded periplasmic space
A	0042597	cellular_component	periplasmic space
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CA A 801

Chain	Residue
A	GLU185
A	ASN263
A	ASP308
A	PQQ1800
A	TFB1810

---

site_id	AC2
Number of Residues	21
Details	BINDING SITE FOR RESIDUE HEC A 802

Chain	Residue
A	CYS607
A	HIS608
A	PRO620
A	MET625
A	TYR629
A	LEU633
A	PHE636
A	PRO641
A	ALA642
A	ARG645
A	GLY646
A	MET647
A	PRO648
A	PHE650
A	HOH2067
A	HOH2541
A	HOH2726
A	ARG67
A	GLN435
A	ASN603
A	CYS604

---

site_id	AC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE TFB A 1810

Chain	Residue
A	CYS116
A	CYS117
A	GLU185
A	TRP267
A	ASP308
A	PRO389
A	TRP440
A	CA801
A	PQQ1800
A	HOH2840

---

site_id	AC4
Number of Residues	24
Details	BINDING SITE FOR RESIDUE PQQ A 1800

Chain	Residue
A	GLU70
A	CYS116
A	CYS117
A	VAL120
A	ARG122
A	THR167
A	GLY182
A	GLY183
A	ALA184
A	GLU185
A	THR243
A	TRP245
A	ASN263
A	ASP308
A	LYS335
A	ASN394
A	TRP395
A	TRP479
A	GLY543
A	VAL544
A	CA801
A	TFB1810
A	HOH1845
A	HOH1856

---

site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 1820

Chain	Residue
A	GLU474
A	HIS475
A	ARG499
A	TYR503
A	LYS510
A	HOH1866
A	HOH2611

---

site_id	AC6
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GOL A 1823

Chain	Residue
A	TRP541
A	ARG550
A	THR552
A	ARG554
A	GLN555
A	GLY617
A	ASN618
A	HOH1913
A	HOH1945
A	HOH2575

---

site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE GOL A 1824

Chain	Residue
A	HOH2447
A	HOH2635

---

Functional Information from PROSITE/UniProt

site_id	PS00364
Number of Residues	22
Details	BACTERIAL_PQQ_2 Bacterial quinoprotein dehydrogenases signature 2. WdsmtFDaelNTMYVgtGngSP

Chain	Residue	Details
A	TRP245-PRO266

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"11714714","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	11
Details	Binding site: {"evidences":[{"source":"PubMed","id":"11714714","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1KB0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Binding site: {"description":"covalent","evidences":[{"source":"PubMed","id":"11714714","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1KB0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"11714714","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1KB0","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1g72

Chain	Residue	Details
A	ASP308

---