1K89
K89L MUTANT OF GLUTAMATE DEHYDROGENASE
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004352 | molecular_function | glutamate dehydrogenase (NAD+) activity |
| A | 0004353 | molecular_function | glutamate dehydrogenase [NAD(P)+] activity |
| A | 0004354 | molecular_function | glutamate dehydrogenase (NADP+) activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006520 | biological_process | amino acid metabolic process |
| A | 0006537 | biological_process | glutamate biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016639 | molecular_function | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor |
| A | 0019552 | biological_process | glutamate catabolic process via 2-hydroxyglutarate |
| A | 0055114 | biological_process | obsolete oxidation-reduction process |
Functional Information from PROSITE/UniProt
| site_id | PS00074 |
| Number of Residues | 14 |
| Details | GLFV_DEHYDROGENASE Glu / Leu / Phe / Val dehydrogenases active site. LpmGGAKgGsdfDP |
| Chain | Residue | Details |
| A | LEU119-PRO132 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor => ECO:0000255|PROSITE-ProRule:PRU10011, ECO:0000269|PubMed:8263917 |
| Chain | Residue | Details |
| A | GLY126 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:8263917 |
| Chain | Residue | Details |
| A | GLY90 | |
| A | ALA111 | |
| A | ASP114 | |
| A | GLY381 | |
| A | ASP165 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000305 |
| Chain | Residue | Details |
| A | VAL241 | |
| A | GLY210 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | SITE: Important for catalysis => ECO:0000250 |
| Chain | Residue | Details |
| A | LEU166 |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 2 |
| Details | M-CSA 579 |
| Chain | Residue | Details |
| A | GLY126 | electrostatic stabiliser, proton acceptor, proton donor |
| A | LEU166 | proton acceptor, proton donor |
