1K4M
Crystal structure of E.coli nicotinic acid mononucleotide adenylyltransferase complexed to deamido-NAD
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000309 | molecular_function | nicotinamide-nucleotide adenylyltransferase activity |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004515 | molecular_function | nicotinate-nucleotide adenylyltransferase activity |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0009165 | biological_process | nucleotide biosynthetic process |
| A | 0009435 | biological_process | NAD+ biosynthetic process |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0034355 | biological_process | NAD+ biosynthetic process via the salvage pathway |
| A | 0034628 | biological_process | 'de novo' NAD+ biosynthetic process from L-aspartate |
| A | 0070566 | molecular_function | adenylyltransferase activity |
| B | 0000309 | molecular_function | nicotinamide-nucleotide adenylyltransferase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004515 | molecular_function | nicotinate-nucleotide adenylyltransferase activity |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0009165 | biological_process | nucleotide biosynthetic process |
| B | 0009435 | biological_process | NAD+ biosynthetic process |
| B | 0016779 | molecular_function | nucleotidyltransferase activity |
| B | 0034355 | biological_process | NAD+ biosynthetic process via the salvage pathway |
| B | 0034628 | biological_process | 'de novo' NAD+ biosynthetic process from L-aspartate |
| B | 0070566 | molecular_function | adenylyltransferase activity |
| C | 0000309 | molecular_function | nicotinamide-nucleotide adenylyltransferase activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0004515 | molecular_function | nicotinate-nucleotide adenylyltransferase activity |
| C | 0009058 | biological_process | biosynthetic process |
| C | 0009165 | biological_process | nucleotide biosynthetic process |
| C | 0009435 | biological_process | NAD+ biosynthetic process |
| C | 0016779 | molecular_function | nucleotidyltransferase activity |
| C | 0034355 | biological_process | NAD+ biosynthetic process via the salvage pathway |
| C | 0034628 | biological_process | 'de novo' NAD+ biosynthetic process from L-aspartate |
| C | 0070566 | molecular_function | adenylyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 34 |
| Details | BINDING SITE FOR RESIDUE NAD A 601 |
| Chain | Residue |
| A | PHE8 |
| A | ARG46 |
| A | TYR84 |
| A | THR85 |
| A | PHE104 |
| A | ILE106 |
| A | GLY107 |
| A | ASP109 |
| A | SER110 |
| A | TRP117 |
| A | TYR118 |
| A | GLY9 |
| A | ARG134 |
| A | PHE177 |
| A | ILE179 |
| A | HOH605 |
| A | HOH608 |
| A | HOH612 |
| A | HOH615 |
| A | HOH616 |
| A | HOH617 |
| A | HOH618 |
| A | GLY10 |
| A | HOH635 |
| A | HOH663 |
| A | HOH698 |
| A | HOH736 |
| A | HOH754 |
| A | THR11 |
| A | PHE12 |
| A | GLY18 |
| A | HIS19 |
| A | ASN40 |
| A | HIS45 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE CIT A 604 |
| Chain | Residue |
| A | ARG46 |
| A | ASP109 |
| A | ARG134 |
| A | SER180 |
| A | ALA181 |
| A | THR182 |
| A | ARG185 |
| A | HOH608 |
| A | HOH615 |
| A | HOH620 |
| A | HOH622 |
| A | HOH736 |
| A | HOH765 |
| site_id | AC3 |
| Number of Residues | 35 |
| Details | BINDING SITE FOR RESIDUE NAD B 602 |
| Chain | Residue |
| B | PHE8 |
| B | GLY9 |
| B | GLY10 |
| B | THR11 |
| B | PHE12 |
| B | GLY18 |
| B | HIS19 |
| B | ASN40 |
| B | HIS45 |
| B | ARG46 |
| B | TYR84 |
| B | THR85 |
| B | PHE104 |
| B | ILE106 |
| B | GLY107 |
| B | ASP109 |
| B | SER110 |
| B | TRP117 |
| B | TYR118 |
| B | ARG133 |
| B | ARG134 |
| B | PHE177 |
| B | ILE179 |
| B | HOH607 |
| B | HOH608 |
| B | HOH611 |
| B | HOH614 |
| B | HOH627 |
| B | HOH640 |
| B | HOH644 |
| B | HOH663 |
| B | HOH697 |
| B | HOH710 |
| B | HOH749 |
| B | HOH766 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE CIT B 605 |
| Chain | Residue |
| B | ARG46 |
| B | ASP109 |
| B | ARG134 |
| B | SER180 |
| B | ALA181 |
| B | THR182 |
| B | ARG185 |
| B | HOH611 |
| B | HOH621 |
| B | HOH631 |
| B | HOH644 |
| B | HOH749 |
| B | HOH772 |
| site_id | AC5 |
| Number of Residues | 35 |
| Details | BINDING SITE FOR RESIDUE NAD C 603 |
| Chain | Residue |
| C | PHE12 |
| C | GLY18 |
| C | HIS19 |
| C | ASN40 |
| C | HIS45 |
| C | ARG46 |
| C | TYR84 |
| C | THR85 |
| C | PHE104 |
| C | ILE106 |
| C | GLY107 |
| C | ASP109 |
| C | SER110 |
| C | TRP117 |
| C | TYR118 |
| C | ARG133 |
| C | ARG134 |
| C | PHE177 |
| C | ILE179 |
| C | HOH608 |
| C | HOH609 |
| C | HOH611 |
| C | HOH613 |
| C | HOH617 |
| C | HOH620 |
| C | HOH637 |
| C | HOH646 |
| C | HOH665 |
| C | HOH680 |
| C | HOH701 |
| C | HOH762 |
| C | PHE8 |
| C | GLY9 |
| C | GLY10 |
| C | THR11 |
| site_id | AC6 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE CIT C 606 |
| Chain | Residue |
| C | ARG46 |
| C | ASP109 |
| C | ARG134 |
| C | SER180 |
| C | ALA181 |
| C | THR182 |
| C | ARG185 |
| C | HOH609 |
| C | HOH611 |
| C | HOH618 |
| C | HOH762 |
