Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004517 | molecular_function | nitric-oxide synthase activity |
| A | 0006809 | biological_process | nitric oxide biosynthetic process |
| A | 0020037 | molecular_function | heme binding |
| B | 0004517 | molecular_function | nitric-oxide synthase activity |
| B | 0006809 | biological_process | nitric oxide biosynthetic process |
| B | 0020037 | molecular_function | heme binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT A 1860 |
| Chain | Residue |
| A | ILE419 |
| A | TRP587 |
| A | VAL649 |
| A | HEM750 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT B 2860 |
| Chain | Residue |
| B | HOH109 |
| B | GLY417 |
| B | TRP587 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 900 |
| Chain | Residue |
| B | CYS326 |
| B | CYS331 |
| A | CYS326 |
| A | CYS331 |
| site_id | AC4 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE HEM A 750 |
| Chain | Residue |
| A | HOH25 |
| A | HOH47 |
| A | HOH133 |
| A | TRP409 |
| A | CYS415 |
| A | MET570 |
| A | PHE584 |
| A | SER585 |
| A | TRP587 |
| A | GLU592 |
| A | TRP678 |
| A | PHE704 |
| A | TYR706 |
| A | H4B1760 |
| A | ARV1780 |
| A | ACT1860 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE H4B A 1760 |
| Chain | Residue |
| A | HOH25 |
| A | HOH167 |
| A | SER334 |
| A | ARG596 |
| A | VAL677 |
| A | TRP678 |
| A | HEM750 |
| B | PHE691 |
| B | HIS692 |
| B | GLN693 |
| site_id | AC6 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE ARV A 1780 |
| Chain | Residue |
| A | HOH4 |
| A | GLN478 |
| A | TYR562 |
| A | PRO565 |
| A | VAL567 |
| A | PHE584 |
| A | SER585 |
| A | GLY586 |
| A | TRP587 |
| A | TYR588 |
| A | GLU592 |
| A | ASP597 |
| A | HEM750 |
| site_id | AC7 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE HEM B 750 |
| Chain | Residue |
| B | HOH32 |
| B | HOH76 |
| B | HOH176 |
| B | HOH187 |
| B | TRP409 |
| B | CYS415 |
| B | PHE584 |
| B | TRP587 |
| B | GLU592 |
| B | TRP678 |
| B | TYR706 |
| B | H4B2760 |
| B | ARV2780 |
| site_id | AC8 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE H4B B 2760 |
| Chain | Residue |
| A | TRP676 |
| A | PHE691 |
| A | HIS692 |
| B | HOH32 |
| B | HOH64 |
| B | HOH173 |
| B | SER334 |
| B | ARG596 |
| B | VAL677 |
| B | TRP678 |
| B | HEM750 |
| site_id | AC9 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE ARV B 2780 |
| Chain | Residue |
| B | HOH76 |
| B | GLN478 |
| B | TYR562 |
| B | PRO565 |
| B | ALA566 |
| B | VAL567 |
| B | PHE584 |
| B | SER585 |
| B | GLY586 |
| B | TRP587 |
| B | TYR588 |
| B | GLU592 |
| B | ASP597 |
| B | HEM750 |
Functional Information from PROSITE/UniProt
| site_id | PS60001 |
| Number of Residues | 8 |
| Details | NOS Nitric oxide synthase (NOS) signature. RCVGRIqW |
| Chain | Residue | Details |
| A | ARG414-TRP421 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | SER334 | |
| B | SER334 | |
| B | GLN478 | |
| B | TRP587 | |
| B | TYR588 | |
| B | GLU592 | |
| B | VAL677 | |
| B | TRP678 | |
| B | PHE691 | |
| B | TYR706 | |
| A | GLN478 | |
| A | TRP587 | |
| A | TYR588 | |
| A | GLU592 | |
| A | VAL677 | |
| A | TRP678 | |
| A | PHE691 | |
| A | TYR706 | |
| Chain | Residue | Details |
| A | CYS415 | |
| B | CYS415 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 3nos |
| Chain | Residue | Details |
| A | CYS415 | |
| A | TRP587 | |
| A | GLU592 | |
| A | ARG418 | |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 3nos |
| Chain | Residue | Details |
| B | CYS415 | |
| B | TRP587 | |
| B | GLU592 | |
| B | ARG418 | |
