Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0008902 | molecular_function | hydroxymethylpyrimidine kinase activity |
| A | 0008972 | molecular_function | phosphomethylpyrimidine kinase activity |
| A | 0009228 | biological_process | thiamine biosynthetic process |
| A | 0009229 | biological_process | thiamine diphosphate biosynthetic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0008902 | molecular_function | hydroxymethylpyrimidine kinase activity |
| B | 0008972 | molecular_function | phosphomethylpyrimidine kinase activity |
| B | 0009228 | biological_process | thiamine biosynthetic process |
| B | 0009229 | biological_process | thiamine diphosphate biosynthetic process |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016740 | molecular_function | transferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2003 |
| Chain | Residue |
| A | ASP105 |
| A | THR106 |
| A | GLU142 |
| A | LYS176 |
| A | GLY212 |
| A | SO42005 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 2004 |
| Chain | Residue |
| B | LYS176 |
| B | GLY212 |
| B | SO42006 |
| B | ASP105 |
| B | THR106 |
| B | GLU142 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2005 |
| Chain | Residue |
| A | THR208 |
| A | HIS209 |
| A | GLY210 |
| A | HMH2001 |
| A | SO42003 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 2006 |
| Chain | Residue |
| B | THR208 |
| B | GLY210 |
| B | THR211 |
| B | GLY212 |
| B | HMH2002 |
| B | SO42004 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE HMH A 2001 |
| Chain | Residue |
| A | GLY11 |
| A | THR12 |
| A | GLU44 |
| A | LYS111 |
| A | CYS213 |
| A | SO42005 |
| A | HOH2023 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE HMH B 2002 |
| Chain | Residue |
| B | GLY11 |
| B | THR12 |
| B | GLU44 |
| B | MET80 |
| B | CYS213 |
| B | SO42006 |
| B | HOH2014 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11839308","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1jxh |
| Chain | Residue | Details |
| A | GLY210 | |
| A | LYS176 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1jxh |
| Chain | Residue | Details |
| B | GLY210 | |
| B | LYS176 | |
| site_id | MCSA1 |
| Number of Residues | 6 |
| Details | M-CSA 670 |
| Chain | Residue | Details |
| A | LYS176 | electrostatic stabiliser |
| A | THR208 | metal ligand |
| A | GLY210 | electrostatic stabiliser |
| A | THR211 | electrostatic stabiliser |
| A | GLY212 | electrostatic stabiliser |
| A | CYS213 | electrostatic stabiliser |
| site_id | MCSA2 |
| Number of Residues | 6 |
| Details | M-CSA 670 |
| Chain | Residue | Details |
| B | LYS176 | electrostatic stabiliser |
| B | THR208 | metal ligand |
| B | GLY210 | electrostatic stabiliser |
| B | THR211 | electrostatic stabiliser |
| B | GLY212 | electrostatic stabiliser |
| B | CYS213 | electrostatic stabiliser |
